Scope: The aim concerning this paper was to climax the stages of Chronic Lymphocytic Leukemia type B (CLL-B), which did not meet the standard situation criteria for diseased hematological diseases due to mutations in the P-53 deoxyribonucleic acid, with progress to Richter Syndrome.Method: The frequency of p-53 protein expression in 85 victims diagnosed accompanying CLL was analyzed apiece Enzyme Linked Immune-Absorbent Assay (ELISA) technique to investigate the connection of this protein to the entertainment industry of the disease, as well as the affect response to situation and survival. Results: The frequency of raised positivity of the protein accompanying the modified structure, the isoform, p-53 in type B CLL, was 17% in the 85 cases originally included in the study. The portion of p-53 protein isoforms, positive having a high temperature value, with very extreme values, 50, 60, individually 140 µg / dl was found in the percentage of 3.5% accompanying the transformation of CLL into non-Hodgkin's diseased lymphomas, (NHL) type Diffuse Large Lymphoma, (DLL) or in Mantle Lymphoma, from Richter syndrome.Conclusions: In the context of a assorted condition such as LL-B, this low and safe arrangement, ELISA seems to provide a beneficial prognostic tool worthy identifying patients the one can be thought-out candidates for therapeutic, target, personalized blueprints.
Author(s) Details:
Aurelian Udristioiu,
Faculty
of General Nursing, (AMG), Titu Maiorescu University of Bucharest, Targu Jiu
Branch, Romania.
Adina
Martin,
Faculty
of General Nursing, (AMG), Titu Maiorescu University of Bucharest, Targu Jiu
Branch, Romania.
Alexandru Giubelan,
Faculty of General Nursing, (AMG), Titu Maiorescu University of
Bucharest, Targu Jiu Branch, Romania.
Liviu Martin,
Faculty of General Nursing, (AMG), Titu Maiorescu University of
Bucharest, Targu Jiu Branch, Romania.
Buciu
Gabriel,
Faculty
of General Nursing, (AMG), Titu Maiorescu University of Bucharest, Targu Jiu
Branch, Romania.
Adina
Martin,
Faculty
of General Nursing, (AMG), Titu Maiorescu University of Bucharest, Targu Jiu
Branch, Romania.
Papurica Maria Daniela,
Faculty of General Nursing, (AMG), Titu Maiorescu University of Bucharest,
Targu Jiu Branch, Romania.
Delia Nica-Badea,
Faculty of Medical Science and Behaviours, Constantin Brancusi
University, Târgu-Jiu, Romania.
Please see the link here: https://stm.bookpi.org/CIMMS-V6/article/view/8614
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