A Comprehensive Review on Pharmaceutical Nanosuspension - as a Nanotechnology Tool for Solubility Enhancement | Chapter 1 | Challenges and Advances in Pharmaceutical Research Vol. 9

 Generally, depressed bioavailability is one of the important problems associated with poorly dissolved drugs. This becomes more worried problem in the case of drugs which are poorly dissolved in both liquid and non-aqueous publishing. To avoid all these problems, nanotechnology methods have been made acquainted which is gaining much interest in reconstructing the solubility of poorly soluble drugs. Use of nanosuspension arose as a prominent, appealing and promising alternative for efficient childbirth of such type of hydrophobic drugs. It is working for the development of the novel drug formulations and they have emerged as a favorable strategy for improving the solubility of the hydrophobic drugs due to their singular advantages. Bioavailability, stability and solubility of drugs are the determinants that can be revised by the nanosuspension science. Reducing the drug particle size into substitute-micron size leads to a notable increase in the separation rate and they interact with the corpse at sub-natural scales with the large size of specificity, altering pharmacokinetics of drug and reconstructing drug efficacy and security. Nanosupension methods proved to gain maximal healing efficacy accompanying minimal side effects and their singular features have allowed their usage in various portion of drug or other consumable forms. They are commercially prepared by press homogenization, media contents, and emulsification. Extensive efforts are being put into this field to longer their applications in the station specific drug delivery in the way that ocular, pulmonary and parenteral routes. This review item describes the readiness methods, characterization of nanosuspension containing its benefits, displayed formulations and its pharmaceutical requests.

Author(s) Details:

S. Naveen Taj,
Department of Pharmaceutics, Sri Padmavati Mahila Visvavidyalayam, [Women’s University], Tirupati – 517502, Andhra Pradesh [A.P], India.

Y. Kavya,
Sri Padmavati Mahila Visvavidyalayam, Women’s University, India.

T. Chandna Shrinivaasiny,
Sri Padmavati Mahila Visvavidyalayam, Women’s University, India.

M. Dakshayani,
Sri Padmavati Mahila Visvavidyalayam, Women’s University, India.

K. Anitha Lakshmi,
Sri Padmavati Mahila Visvavidyalayam, Women’s University, India.

Please see the link here: https://stm.bookpi.org/CAPR-V9/article/view/8670