Wednesday 30 November 2022

Antibacterial and Antifungal Activity of Carica papaya L. Seed Extracts: A Recent Study| Chapter 9| Challenges and Advances in Pharmaceutical Research Vol. 10

 Antimicrobial powers are abundant in medicinal plants. Many strong and useful cures are derived from medicinal plants, that are used in various nations. Carica papaya roots, crops, bark, seeds, and pulp have existed shown to have therapeutic belongings. It has been used to treat conditions in the way that eczema, warts, sinusitis, cutaneous tubercles, upset stomach, blood pressure, amenorrhoea, and constipation. Carica fruit is a more important medicinal spice that is used as a traditional medicine for the treatment of various disorders all over the world. Carica fruit seeds were approved and rooted in some studies for their productive anthelmintic properties against nematodes found in mammals.  It is a member of the Caricaceae family. Carica fruit (Papaya) seeds were gleaned using a soxhlet apparatus utilizing solvents such as flammable liquid, methanol, and chloroform. The completely clean and antifungal activity of extracts at differing concentrations (50, 100, and 150 μg/ml) was examined using the agar plate diffusion method accompanying three gramme positive, three gramme negative microorganisms, and two fungal species. For antibacterial and antifungal ventures, gentamicin and fluconazole were chosen as standard medicines. Methanol and toxin extracts inhibited gramme negative germs in a more excellent manner than ethanol extract. Ethanol and poison extracts demonstrated a larger district of inhibition (10-15 mm) than methanol extract for gramme helpful microorganisms. Candida albicans exhibited a 15, 16 mm district of inhibition in chloroform and intoxicating extracts at concentrations of 150 μg/ml, respectively. Similarly, Aspergillus niger exhibited a district of inhibition of 11, 13 mm in 150 μg/ml methanol and solvent extracts, respectively. According to the judgments of these investigations, Carica papaya children extracts have very strong antibacterial and antifungal venture in both intoxicating and chloroform extracts.

Author(s) Details:

S. Sundar,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

K. Padmalatha,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

A. Jayarami Reddy,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

A. Bhavana,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

N. K. S. Neeraja,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

S. Jaya Sai Keertana,
Department of Pharmacology, Vijaya Institute of Pharmaceutical Sciences for Women, Enikepadu, Vijayawada, Krishna District, Andhra Pradesh, India.

Please see the link here: https://stm.bookpi.org/CAPR-V10/article/view/8803

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