Cancer is a ailment which is harshly effecting the global human community. There is always a loyal demand for new therapies to treat and forestall this life-threatening disease. Scientific and research interest is illustration its consideration towards naturally derivative compounds, as they are considered to have less poisonous side effects compared to current situations such as a destructive agent, radiation etc. Medicinal plant Tridax procumbens produces commonly occurring secondary metabolites that is being investigated for the anticancer actions against A549 (human lung tumor cell line), Hep G2 (human liver carcinoma container line) leading to the happening of new clinical drug.MTT and trypan sky dye exclusion assays were used to assess the anticancer action of T.procumbens ethanol, acetone, and liquid leaf extracts on selected human malignant cell lines. The MTT assay relies on the skill of viable containers' mitochondrial enzymes to convert the yellow soluble seasoning MTT to the purple sad insoluble formazan precipitate, that is then characterized spectrophotometrically at 570 nm. The Trypan blue assay depends cell staining. Cells are then included under a microscope using a hemocytometer, and non-practicable cells are tainted blue while viable containers remain spotless.The aqueous leaf extract of T. procumbens has not proved any anticancer activity. However, acetone and flammable liquid leaf extracts of T. procumbens has shown forceful anticancer activity on A549 (human alveolus cancer container line), Hep G2 (human liver carcinoma cell line).T. procumbens examined for anticancer potential by MTT assay and trypan blue forbiddance assay. The acetone and ethanol leaf extracts of T. procumbens have proved potent anticancer activity on picked human cell lines.
Author(s) Details:
Pittu Vishnu Priya,
Department
of Pharmaceutical Biotechnology, Joginpally B.R Pharmacy College, Yenkapally
(V), Moinabad (M), Telangana, Hyderabad-500 076, India.
A.
V. S. S. S. Gupta,
Department
of Pharmacology, Joginpally B.R Pharmacy College, Yenkapally (V), Moinabad (M),
Telangana, Hyderabad-500 076, India.
A. Srinivasa Rao,
Department of Pharmacology, Bhaskar Pharmacy College, Yenkapally
(V), Moinabad (M), Telangana, Hyderabad-500 076, India.
Please see the link here: https://stm.bookpi.org/CAPR-V10/article/view/8828
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