This study demonstrates the potential of using synthetic polyelectrolyte nanofilms for efficient adhesion and mesenchymal stem cell culturing in both animals and humans (MSCs). The characteristics of single-layer and multilayer synthetic films' development and cytotoxic effects were discovered. It has been demonstrated that the characteristics of the surface these cells come into direct contact with during cultivation matter to MSCs. Under deprivation conditions, single-layer polyethyleneimine (PEI) films with immobilised growth factors produce the best outcomes for MSC development, which may be crucial for cell treatment.
Author(s) Details:
Dmitriy A. Reshetnikov,
Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Maria G. Fomkina,
Institute of Theoretical and Experimental Biophysics of the Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Lyudmila M. Mezhevikina,
Institute of Cell Biophysics of the Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Please see the link here: https://stm.bookpi.org/RABS-V7/article/view/8045
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