Since they represent a cell's functional output, proteins are the most useful indicators of how a cell is functioning. Systematic analyses of the human proteome from both body fluids and tissue samples may be a potent and dynamic strategy for better understanding a variety of cancers where conventional methods of diagnosis may not be sufficient. Cells in their healthy, disease-free states may exhibit changes in their protein compositions. The basic knowledge regarding the underlying pathophysiology of a disease can be expanded by further comparing them with that of the afflicted condition. Proteomics has made great achievements in revealing fundamental biological processes and advancing our understanding of some complex biological phenomena connected to some serious disorders. In order to understand the pathophysiology of some diseases, numerous body fluids and tissue samples have been subjected to several proteome investigations. This chapter will focus on such research. Researchers have employed a variety of body fluids, including plasma, urine, sputum, CSF, seminal fluid, cervicovaginal fluid, etc., as well as different tissues, including those from the brain, breast, liver, ovary, vagina, etc., to study disorders related to these tissues. Proteomic techniques will also continue to grow and be improved upon, ushering healthcare into a new era of early diagnosis, prognosis, and ultimately successful treatment of these human cancers.
Author(s) Details:
Rahul Suman,
Department of Microbiology, Panjab University, Chandigarh-160014, India.
Aditi Chauhan,
Department of Microbiology, Panjab University, Chandigarh-160014, India.
Thomson Soni,
Department of Microbiology, Panjab University, Chandigarh-160014, India.
Vijay Prabha,
Department of Microbiology, Panjab University, Chandigarh-160014, India.
Please see the link here: https://stm.bookpi.org/CPMS-V9/article/view/8018
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