Tuesday 30 August 2022

Mechanisms of Antimicrobial Resistance in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)| Chapter 9 | Challenges and Advances in Pharmaceutical Research Vol. 6

 In the medical field, antibiotics are frequently used to treat a variety of infectious disorders. High death rates, rising healthcare costs, and decreasing productivity have all been linked to antimicrobial resistance. The chapter sought to highlight the most recent mechanisms and causes of antibiotic resistance in soronavirus-2, which causes severe acute respiratory syndrome (SARS-CoV-2). The development of antibiotic-resistant bacteria is largely caused by the abuse of antibiotics and other socioeconomic factors.  Investigations found that despite the fact that only 10% to 15% of infected SARS-CoV-2 cases had secondary bacterial infection, healthcare systems are treating all SARS-CoV-2 infections with antibiotics, even when the symptoms are moderate. The evolution of antibiotic resistance is also being exacerbated by overworked healthcare systems, inadequate infection control procedures, and increased production of personal protective equipment (PPE). Emerging COVID-19 genetic variations have been shown to reduce the effectiveness of many COVID-19 vaccinations, demonstrating the necessity of routine booster shots. In healthcare settings, antibiotic stewardship should be encouraged with the appropriate flexibility as necessary.


Author(s) Details:

Mohamed Raslan,
Drug Research Centre, Cairo, Egypt.

M. S. Eslam,
Drug Research Centre, Cairo, Egypt.

A. R. Sara,
Drug Research Centre, Cairo, Egypt.

Nagwa A. Sabri,
Department of Clinical Pharmacy, Faculty of Pharmacy- Ain Shams University, Cairo, Egypt.

Please see the link here: https://stm.bookpi.org/CAPR-V6/article/view/8097

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