Friday, 29 April 2022

Possible Anti-cardiovascular Boosting Properties of Sphenostylis stenocarpa Seed Oil and Milk on Salt Loading-induced Hypertension in Rats | Chapter 06 | Current Topics on Chemistry and Biochemistry Vol. 1

 Legumes have been demonstrated to have high nutraceutical potential, making them a good source of nutrients that are good for human health. Cardiovascular diseases (CVDs), which have been one of the leading causes of death in middle and high-income countries, can be avoided by protecting the heart from malfunctioning. In 2015, 82 percent of the 17 million early deaths (before the age of 70) owing to noncommunicable illnesses occurred in middle and high income nations, with CVDs accounting for 37 percent. The primary prevention of risk factors is the most effective method for preventing cardiovascular disease. Most cardiovascular illnesses can be avoided by implementing population-wide programmes to address behavioural risk factors such cigarette use, poor diet and obesity, physical inactivity, and problematic alcohol consumption. People who have cardiovascular diseases or are at high cardiovascular risk (due to the existence of one or more risk factors such as hypertension, diabetes, hyperlipidemia, or previously established disease) require early detection and therapy, which may include counselling and medications. Sphenostylis stenocarpa (Hochst. ex. A. Rich) Harms is an orphan legume crop whose oil and milk considerably (p 0.05) reduced the atherogenic index of plasma (AIP), a robust marker for predicting the risk of cardiovascular disease, when given to hypertensive albino rats. Rats were given a saturated NaCl solution to produce hypertension. The rats were given varied concentrations of the extracted oil and milk. It was discovered that Sphenostylis stenocarpa seed has a low glycaemic index and that it reduced AIP considerably (p 0.05) at various doses and times.



Author(S) Details


Nwankwo Michael Olisa
Department of Biochemistry, Faculty of Biological Sciences, University of Nigeria, Nsukka, Nigeria.

Ogbonna Innocent Okonkwo
Department of Microbiology, Federal University of Agriculture, Makurdi, Nigeria.

Yila Lakabra David
Department of Biochemistry, Federal University of Agriculture, Makurdi, Nigeria.

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