Determination of Quantitative Macular Perfusion Assessment in Surgical and Non-surgical Cases of Early-stage Myopic Traction Maculopathy | Chapter 07 | New Horizons in Medicine and Medical Research Vol. 5

 The goal of this study was to compare quantitative changes in macular perfusion in normal eyes, healthy highly myopic eyes, eyes with myopic foveoschisis (MF)/foveoretinal detachment (FRD) that had not been surgically treated, and eyes with early stages of macular traction maculopathy (MTM) and fully resolved myopic FRD that had been surgically treated.

Between October 2015 and April 2021, 118 eyes (104 persons) were studied in a retrospective, sequential, comparative, interventional, single-surgeon, case-control study. Normal emmetropic eyes (control emmetropia, n = 25), healthy myopic eyes (control high myopia, n = 20), eyes with MF/FRD not treated surgically (non-surgical observational group, n = 28), and structurally fully resolved myopic eyes with FRD treated surgically (surgically treated group, n = 45) were among the participants. Long-term postoperative structural, functional, and perfusional results were assessed using spectral-domain optical coherence tomography (SD-OCT) and OCT angiography.

According to the findings, the mean evolution time of myopic FRD in the surgical group was 6.2 3.6 months. The average duration of follow-up was 25.9 10.3 months. The myopic FRD resolution took an average of 4.6 1.9 weeks. The median best-corrected visual acuity improved from 0.90 logarithm of the minimum angle of resolution (logMAR; 0.60–1.00) to 0.30 logMAR (0.09–1.00) in the FRD surgery group, a highly significant improvement (p 0.0001). The results of the quantitative vascular density (VD) evaluations were significantly different between the groups (p 0.001). The non-surgical group had a considerably larger superficial foveal avascular zone (FAZ) area (p 0.0001). Lower postoperative SD-OCT structural findings and higher VD quantification values were closely linked to superior final visual acuity results (p 0.05). The surgical group had a significantly reduced central subfoveal thickness (both p0.05), while the observational group had a significantly higher central subfoveal thickness.

The surgical group had a higher rate of postoperative SD-OCT microstructural abnormalities (91.4%) than the non-surgical group, as well as a high rate of statistically significant VD quantitative deficiencies and FAZ abnormalities, and marked improvement in VD and FAZ in the fully surgically resolved myopic FRD group (p 0.05).

Author(S) Details

Miguel A. Quiroz-Reyes
Retina Specialists Unit at Oftalmologia Integral ABC, Medico Surgical Assistance Institution (non-profit organization). Av. Paseo de las Palmas 735 Suite 303, Lomas de Chapultepec, Alcaldia Miguel Hidalgo, Mexico City 11000, Affiliated to Postgraduate Division Studies at the National Autonomous University of Mexico, Mexico.

Erick A. Quiroz-Gonzalez
Retina Specialists Unit at Oftalmologia Integral ABC, Medico Surgical Assistance Institution (non-profit organization). Av. Paseo de las Palmas 735 Suite 303, Lomas de Chapultepec, Alcaldia Miguel Hidalgo, Mexico City 11000, Affiliated to Postgraduate Division Studies at the National Autonomous University of Mexico, Mexico.

Miguel A. Quiroz-Gonzalez
Retina Specialists Unit at Oftalmologia Integral ABC, Medico Surgical Assistance Institution (non-profit organization). Av. Paseo de las Palmas 735 Suite 303, Lomas de Chapultepec, Alcaldia Miguel Hidalgo, Mexico City 11000, Affiliated to Postgraduate Division Studies at the National Autonomous University of Mexico, Mexico.

Virgilio Lima-Gomez
Juarez Hospital, Public Assistance Institution (non-profit organization), Av. Politecnico Nacional 5160, Colonia Magdalena de las Salinas, Mexico City 07760, Mexico.

View Book:- https://stm.bookpi.org/NHMMR-V5/article/view/6484