The goal of this study was to find out how common thyroid dysfunction, specifically subclinical hypothyroidism (SCH), is in children and adolescents in northern Andhra Pradesh, and how it relates to hyperlipidemia. Thyroid hormone can be provided to lower TSH levels, although the actual cause of TSH elevation is uncertain. Some clinicians regard SCH to be a benign normal fluctuation, and thyroid hormone can be supplemented to lower TSH levels. Age, sex, total triiodothyronine (tT3), total tetraiodothyronine (tT4), thyroid stimulating hormone (TSH), total cholesterol, triglycerides (TGL), LDL, and HDL cholesterol were all evaluated in a retrospective study of 600 participants (Children=272, Adolescents=328) between the ages of 6 and 19. The participants were divided into two groups according to their age (in years), with those aged 6 to 12 years in group I and those aged 12 to 19 years in group II. Thyroid dysfunction was observed in 9.9% of the 272 children and 10.4% of the 328 adolescents that were investigated, respectively. 7.7% of children and 4.9 percent of teenagers were found to have subclinical hypothyroidism. In both groups, females were more affected by thyroid dysfunction than males. SCH individuals showed substantially higher serum levels of total cholesterol, TSH, and TGL (p0.05) than euthyroid participants. In comparison to euthyroids, SCH had statistically significant lower HDL cholesterol values (p0.05). There was no change in total T3, total T4, or LDL cholesterol levels between SCH and euthyroids. Thyroid dysfunction was found to be present in 10.2% of the research participants. 7.7% of children and 4.9 percent of teenagers had SCH, according to the study. Subclinical hypothyroidism (SCH) was the most common thyroid malfunction in our study cohort, with a prevalence of 6.2 percent (both children and adolescents).
Author(S) Details
Prasad DKV
Department of Biochemistry, NRI Institute of Medical Sciences, Sangivalasa, Andhra Pradesh, India.
Prabhakara Rao TS
Department of Paediatrics, Gayatri Vidya Parishad Medical College, Visakhapatnam, Andhra Pradesh, India.
Kiranmai Ch
Department of Biochemistry, NRI Institute of Medical Sciences, Sangivalasa, Andhra Pradesh, India.
View Book:- https://stm.bookpi.org/NHMMR-V5/article/view/6476
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