The population uses crude plant extracts in the form of herbal extracts for the treatment of ailments, including infectious disorders, in herbal medicine. Hundreds of plant genera are used as key sources of potent and effective medications. The goal of this study was to investigate the antibacterial effect of several natural products derived from herbal and spice extracts, as well as to compare the antimicrobial activity of these aqueous and ethanolic extract test items using MIC and MBC as a reference. The current analysis was conducted on five fresh samples from different circumstances. The antibacterial properties of Tripfala, Java plum, Cinnamon, Henna, and Cumin against both gram-positive and gram-negative bacteria were examined using the agar well and disc diffusion methods. Aqueous extracts of selected sample extracts had a higher zone of inhibition or antibacterial activity than ethanolic extracts. Klebsiella sp. demonstrated the lowest sensitivity to Tripfala and Java plum extracts among the five microorganisms tested, despite the fact that these aqueous and ethanolic extracts had substantial antibiotic action against four other microbes. All of the natural compounds had MIC values ranging from 12.5-25.0 ug/ml, whereas the MBC values ranged from 25 to 100.0 ug/ml. There was no change in antibacterial activity during the four-month preservation of these natural plant materials' produced discs. Tripfala and Java Plum may have the potential to be employed as a source of new broad-spectrum oral antibiotics, according to this study.
Author(S) Details
Zakaria Ahmed
Microbiology Department, Technology Wing, Bangladesh Jute Research Institute, Dhaka 1207, Bangladesh.
Taslima Rahman
Microbiology Department, Technology Wing, Bangladesh Jute Research Institute, Dhaka 1207, Bangladesh.
Sanchita Sarker
Biotechnology and Genetic Engineering Faculty, Sylhet Agricultural University, Sylhet-3100, Bangladesh.
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