The goal of this study is to see if dandelion (Taraxacum officinale) can protect you against lead poisoning. Lead is thought to be an oxidative stress inducer in several tissues and organs. Female wistar rats were fed a diet containing 600 mg lead acetate per kilogramme of food (Pb) or a diet containing 20 g fresh dandelion leaves per kilogramme of food (Pb-DD), and then compared to a control group for 6 weeks. The researchers looked into a number of haematological and serum biochemical markers. When compared to the control group, the Pb group had a large decrease in RBC and haemoglobin levels, but a considerable increase in methemoglobin. The Pb-DD group had the same RBC counts and haemoglobin levels as the control group, but the methemoglobin percentage was considerably greater. The activities of AST, ALT, and alkaline phosphate, as well as total bilirubin and uric acid levels, all increased significantly in the Pb group. Except for uric acid, dandelion supplementation has kept all of the preceding biochemical markers within normal limits. However, there were no significant alterations in albumin, cholesterol, creatinine, or calcium concentrations in Pb or Pb-DD treated mice. The Pb-DD-treated group and the control group had no significant changes in histological exams of the liver, kidney, or ovary. Pb, on the other hand, has been linked to cystic formations and vacuolization in the liver, as well as necrosis and microcalcifications in the kidney. Ovarian tissue degradation was also seen in the Pb group, including the absence of corona radiata and granulosa cell death. Finally, adding dendelion to a Pb-contaminated meal reduced metal toxicity in female rats considerably.
Author(S) Details
Mansouri Ouarda
Faculty of Medicine, Laboratory of Animal Ecophysiology, University Badji Mokhtar-Annaba BP 12, Annaba 23000, Algeria.
Cherif Abdennour
Faculty of Sciences, Department of Biology, Laboratory of Animal Ecophysiology, University Badji Mokhtar-Annaba BP 12, Annaba 23000, Algeria.
Kamel Khelili
Faculty of Sciences, Department of Biology, Laboratory of Animal Ecophysiology, University Badji Mokhtar-Annaba BP 12, Annaba 23000, Algeria.
Radia Berredjem
Faculty of Sciences, Department of Biology, Laboratory of Animal Ecophysiology, University Badji Mokhtar-Annaba BP 12, Annaba 23000, Algeria.
Mohamed Salah Boulakoud
Faculty of Sciences, Department of Biology, Laboratory of Animal Ecophysiology, University Badji Mokhtar-Annaba BP 12, Annaba 23000, Algeria.
View Book:- https://stm.bookpi.org/NVBS-V6/article/view/4859
No comments:
Post a Comment