Qualitative assessment of Helicobacter pylori by PCR in the saliva of Male Smokers and Non-Smokers with Chronic Periodontitis | Chapter 14 | Novel Research Aspects in Medicine and Medical Science Vol. 5

 Helicobacter pylori (H. pylori), a rational resident of the pertaining to the stomach environment, has also happened found in the spoken environment of humans. Various studies have befriended the presence of H. pylori in the spoken environment of subjects accompanying periodontitis suggesting that progression of periodontal pocket and redness may favor settling by this bacterium. One of the major risk determinants for periodontitis is smoking. Smokers have raised prevalence and severe in consideration of periodontal disease, in addition to a higher prevalence of premolar loss distinguished to non-smokers. This chapter aims to evaluate the comparative presence of H. pylori in the slobber of smokers and nonsmokers with never-ending periodontitis. A total of 48 male individuals diagnosed accompanying chronic periodontitis (CAL≥5mm) accompanying and without hot habits were enrolled in the study. The unstimulated whole slaver was subjected to H. pylori DNA discovery using real-occasion PCR. The percent closeness of H. pylori DNA among the groups was statistically compared.Periodontal limits (gingival index, plaque index, acute depth, and dispassionate attachment level) were significantly various between smokers and non-smokers distinguished to controls (P =.001). Overall, H. pylori was not detected in controls (100% negative), whereas 5.5% of non-smokers and 13.3% of smokers revealed the presence of H. pylori. The Chi-square test presented a significant difference (P =.003) betwixt smokers and controls; however, it was visualized that the relative differences with the groups could not reach statistical importance. The study revealed that smokers accompanying chronic periodontitis may bother a relatively greater risk of H. pylori presence in the oral crater than non-smokers.

Author(s) Details:

Rajeev Kishore Saxena,
Department of Microbiology, Abhishek I. Mishra Memorial Medical College and Research, Junwani, Bhilai, India.

Abdul Samad Aziz,
Department of Biochemistry, Dr. G. D. Pol Foundation’s YMT Dental College and Hospital, Kharghar, Navi-Mumbai, India.

Madhav Govind Kalekar,
Department of Biochemistry, Grant Medical College and Sir J. J. Group of Hospitals, Byculla, Mumbai, India.

J. P. Milsee Mol,
Department of Biotechnology, Sinhgad College of Science, Pune, India.

Adinath Narayan Suryakar,
FACBI, Registrar, Maharashtra University of Health Sciences, Nashik, India.

Benjamin Tabita,
Department of Dentistry, Grant Medical College and Sir J. J. Group of Hospitals, Byculla, Mumbai, India.

Ravi Vasudev Shirahatti,
Department of Public Health Dentistry, Sinhgad Dental College, Pune, India.

Raghavendra Shrishail Medikeri,
Department of Periodontics, Sinhgad Dental College, Pune, India.

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