New Flavonoids from the Leaves and Stems of Cinnamomum Reticulatum Hayate: Antioxidation and Antiproliferation Assay | Chapter 7 | Novel Aspects on Chemistry and Biochemistry Vol. 2

 The present study checked the anti-burning and anti-increase activity of the two new flavonoids compounds in malignancy cells. Cinnamomum class have been secondhand as important beginnings of traditional medicine, wood, edible crops, spices, and perfumes in China for a long history. Cinnamoum reticulatum  Hayata (Lauraceae) is an native tree class in Taiwan. We further isolated the two flavonoids compounds kaempferol-3-O-(2",4"-di-E-p-coumaroyl)- ∝-L-rhamnopyranoside (1) and kaempferol-3-O-(3",4"-di-E-p-coumaroyl)- ∝-L-rhamnopyranoside (2) from the leaves and stems of C. reticulatum Hayate. The phytochemical traits, antioxidant and cytotoxic activities of two together compounds were evaluated. Kaempferol-3-O-(2",4"-di-E-p-coumaroyl)- ∝-L-rhamnopyranoside (1) and kaempferol-3-O-(3",4"-di-E-p-coumaroyl)- ∝-L-rhamnopyranoside (2) have antiproliferation action in lung malignancy cell line (A549 and NCI-H460) and conscience cancer cell line (MCF-7 and MDA-MB-231). However, (1) displays better antioxidant venture than (2). Our results showed that two together flavonoids from C. reticulatum might have good potential for further happening as chemoprevention or antioxidant remedies. Flavonoids possess antagonistic-oxidative effects as free radical scavengers and metal ion cheaters features associated with the phenolic hydroxyl groups ascribed to ring structures. Intensity of the antioxidant endeavor of a flavonoid strongly depends on allure chemical structure.

Author(s) Details:

Chi-Ming Liu,
Department of Nursing, Tzu Hui Institute of Technology, Pingtung County- 92641, Taiwan.

Hung-Chun Yeh,
Department of Nutrition and Health Sciences, School of Medical and Health Sciences, Fooyin University, Kaohsiung-83102, Taiwan.

Song-Chih Huang,
Department of Creative Product Design, College of Design, Ling Tung University, Taichung-40852, Taiwan

Chung-Yi Chen,
Department of Nutrition and Health Sciences, School of Medical and Health Sciences, Fooyin University, Kaohsiung-83102, Taiwan.

Please see the link here: https://stm.bookpi.org/NACB-V2/article/view/10665