The number of diabetics is growing year by year in the experience and the complications of the ailment are debilitating. Type 2 diabetes is approximately connected to oxidative stress created by waste fat. Oxidative stress has been proved to induce insulin opposition. The objective of this work search out establish the link betwixt the arrangement in phenolic compounds and the antiradical activity of five plants discussing diabetes in the south and in the middle of Benin. Coloration and precipitation processes having to do with each metabolite family were used to recognize secondary metabolites. The Folin Ciocalteu method was used to decide total phenols. Total flavonoids were quantified utilizing the aluminium trichloride technique. The antiradical talent of 2,2-diphenyl-l-picrylhydrazyl(DPPH) was determined. Our results presented that the leaves of three plants contained extreme level of phenolic compounds; Mangifera indica (29.409 mgGAE/g); Parkia biglobosa (26.909mgGAE/g) and Bambusa vulgaris (23.298 mgGAE/gEx). It is the hydro-ethanolic extracts of these three plants that have shown taller antagonistic-radical activities than that of source of nourishment C. Bambusa vulgaris (IC50=0.28mg/mL), Parkia biglobosa (IC50=0.3mg/mL), Mangifera indica (IC50=2.5mg/mL), vitamin C (IC50=3.2 mg/mL). The arrangement in polyphenols and the antiradical activity of these three plants keep justify their duty in the prevention and situation of type 2 diabetes and its snags.
Author(s) Details:
Koukoui Semako Omedine,
Laboratory
of Animal Physiology, Cellular Signalisation and Pharmacology, University of
Sciences Technologies, Engineering and Mathematics, Dassa Zoume, Benin.
Agbangnan
Cokou Pascal,
Laboratory
of Study and Research in Applied Chemistry, Unity of Research and Molecular
Interactions (URIM/LERCA/UAC), Cotonou, Benin.
Please see the link here: https://stm.bookpi.org/COPS-V1/article/view/8962
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