Wednesday, 14 September 2022

Study about Electron Ionization of DNA Bases: A Review | Chapter 11 | New Frontiers in Physical Science Research Vol. 2

 In this work, we show the representative partial ion cross sections at 100 eV, the absolute total ionisation cross sections, and some significant highlights of the fragmentation study. There are no reliable experimental data for the partial and total electron ionisation cross sections of DNA bases, which are crucial for modelling radiation damage to the genetic material of living cells. For the first time, we have used the relative flow method to measure the entire set of absolute partial electron ionisation cross sections for DNA bases up to 500 eV. These partial cross sections are added to get total ion cross sections for all four bases, which are then compared to the only set of measured absolute cross sections and the current theoretical calculations. For the first time, our findings provide precise estimates of the partial and total ion cross sections for these compounds, resolving the discrepancy between theoretical and experimental results. The study of adenine's pieces provides evidence that it originated in space. The idea that adenine is a pentamer of HCN formed by successive addition of HCN units during molecular cloud collapse or in a variety of other astrophysical environments is supported by the observation of successive loss of HCN units and relatively high partial cross sections for the associated ions from adenine base.


Author(s) Details:

Mohammad Atiqur Rehman,
Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai - 400005, India.

E. Krishnakumar,
Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai - 400005, India.

Please see the link here: https://stm.bookpi.org/NFPSR-V2/article/view/8210

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