Thursday 30 June 2022

Histopathological Pattern of Endometrium in Abnormal Uterine Bleeding: A Prospective Study | Chapter 7 | Current Practice in Medical Science Vol. 3

By examining histological results in endometrial tissue samples, the current study establishes the most prevalent age group and frequent pathology producing abnormal uterine bleeding.

Abnormal uterine bleeding is one of the most common presenting symptoms in the gynaecology outpatient department (AUB). Unusual uterine bleeding for which there is no known cause is referred to as "dysfunctional uterine haemorrhage." For individuals who have abnormal uterine bleeding, it is essential to assess the endometrium's histological appearance. A beneficial initial step in the diagnosis of DUB may be an endometrial biopsy. This prospective research was conducted in the departments of pathology at Bhaskar Medical College and Satya Diagnostic Center in Hyderabad, Telangana State, on patients who presented with abnormal uterine haemorrhage. The research lasted for a total of two years, from June 2014 to November 2016. For the final analysis, 150 endometrial lesions with histopathological diagnoses were chosen. The dilatation and curettage (D&C) procedure was used to collect all of the endometrial samples included in the study. The patients' ages varied from 21 to 78 years old, with a mean of 49.5 years. Endometrial polyp, complex hyperplasia without atypia, endometrial cancer, pill endometrium, complex hyperplasia with atypia, endometritis, atrophic endometrium, and adenomatous hyperplasia were among the other patterns found. Age pattern and endometrial causes of DUB were statistically significant with a P value 0.05. In order to rule out cancer, a thorough histopathological examination of the endometrium should be performed on women who report with abnormal uterine bleeding, especially beyond the age of 40. In situations of dysfunctional uterine haemorrhage, it is helpful for diagnosis, to evaluate treatment response, and to understand the pathological incidence of organic lesions before surgery. In different types of AUB, D&C shows endometrial patterns and also aids in ruling out any organic disease. The endometrium should thus be histopathologically examined in women over 40 to rule out preneoplastic lesions and cancer.

Author(s) Details:

V. Vijay Sreedhar,
Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

Ch. Jyothi,
Gandhi Medical College, Secunderabad, Telangana State, India.

M. Narsing Rao,
Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

V. Sailaja,
Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

M. N. P. Charan Paul,
Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

G.Vijaya Lakshmi,
Department of Obg and Gynecology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

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