Thursday, 30 June 2022

A Clinico-histopathological Analysis on Abnormal Uterine Bleeding | Chapter 14 | Current Practice in Medical Science Vol. 3

The objective of successful care and a better resolution of the issue is the accurate analysis of endometrial samples and localisation of intrauterine lesions. The diagnostic gold standard for the diagnosis of endometrial pathology continues to be the histological features of endometrial biopsy material as evaluated by light microscopy. Patients and gynaecologists frequently deal with abnormal uterine bleeding (AUB). It has a detrimental effect on women's psychological health and quality of life. As one of the causes of anaemia, it is particularly important in poorer nations. Without tissue identification, abnormal uterine bleeding (AUB) therapy is inadequate, especially in perimenopausal and postmenopausal women. Light microscopy-based histological analysis of endometrial biopsy material is still used to make the diagnosis of endometrial pathology. This investigation was prospective and observational. The study included a total of 359 women who were over 45 years old, had abnormal uterine bleeding, and required endometrial curettage. With a p value of 0.01, a significant correlation between the histopathological pattern and hypertension was discovered. Patients with atrophic endometrium, endometrial hyperplasia, and endometrial cancer had higher rates of hypertension (12 out of 20, 68 out of 96, and 14 out of 23 patients, respectively). Endometrial hyperplasia was seen in 68 out of 116 individuals with hypertension. We discovered that multiparous women had the highest prevalence of AUB. The majority of individuals with AUB had endometrial hyperplasia, according to clinicohistopathological examination.


Author(s) Details:

Y. Anupama Suresh,
Department of OBG, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, India.

Y. V. Suresh,
Department of Anesthesiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, India.

Prachi Jain,
Department of OBG, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, India.

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