Histopathological Pattern of Endometrium in Abnormal Uterine Bleeding: A Prospective Study | Chapter 7 | Current Practice in Medical Science Vol. 3

By examining histological results in endometrial tissue samples, the current study establishes the most prevalent age group and frequent pathology producing abnormal uterine bleeding.

Abnormal uterine bleeding is one of the most common presenting symptoms in the gynaecology outpatient department (AUB). Unusual uterine bleeding for which there is no known cause is referred to as "dysfunctional uterine haemorrhage." For individuals who have abnormal uterine bleeding, it is essential to assess the endometrium's histological appearance. A beneficial initial step in the diagnosis of DUB may be an endometrial biopsy. This prospective research was conducted in the departments of pathology at Bhaskar Medical College and Satya Diagnostic Center in Hyderabad, Telangana State, on patients who presented with abnormal uterine haemorrhage. The research lasted for a total of two years, from June 2014 to November 2016. For the final analysis, 150 endometrial lesions with histopathological diagnoses were chosen. The dilatation and curettage (D&C) procedure was used to collect all of the endometrial samples included in the study. The patients' ages varied from 21 to 78 years old, with a mean of 49.5 years. Endometrial polyp, complex hyperplasia without atypia, endometrial cancer, pill endometrium, complex hyperplasia with atypia, endometritis, atrophic endometrium, and adenomatous hyperplasia were among the other patterns found. Age pattern and endometrial causes of DUB were statistically significant with a P value 0.05. In order to rule out cancer, a thorough histopathological examination of the endometrium should be performed on women who report with abnormal uterine bleeding, especially beyond the age of 40. In situations of dysfunctional uterine haemorrhage, it is helpful for diagnosis, to evaluate treatment response, and to understand the pathological incidence of organic lesions before surgery. In different types of AUB, D&C shows endometrial patterns and also aids in ruling out any organic disease. The endometrium should thus be histopathologically examined in women over 40 to rule out preneoplastic lesions and cancer.

Author(s) Details:

V. Vijay Sreedhar,

Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

Ch. Jyothi,

Gandhi Medical College, Secunderabad, Telangana State, India.

M. Narsing Rao,

Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

V. Sailaja,

Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

M. N. P. Charan Paul,

Department of Pathology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

G.Vijaya Lakshmi,

Department of Obg and Gynecology, Bhaskar Medical College, Ranga Reddy District, Telangana State, India.

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Determination of Clinico-epidemiological Profile of Abnormal Uterine Bleeding among Women of Reproductive Age Group | Chapter 16 | Recent Developments in Medicine and Medical Research Vol. 5

 Background: In underdeveloped countries, abnormal uterine bleeding (AUB) is a common reason for women of all ages to consult a gynaecologist, and it is one of the most debilitating menstrual issues that leads to a hysterectomy. The researchers wanted to examine at the patients' clinical and demographic parameters, as well as the AUB pattern.

An observational study was conducted at the department of obstetrics and gynaecology at the DR Rammanohar Lohia institute of medical sciences in Lucknow, Uttar Pradesh, from August 2018 to July 2019. All women in their reproductive years who experienced symptoms of irregular uterine bleeding were included in the study.

The bulk of the women were between the ages of 30 and 40 (37.50 percent). The majority of the women (60 percent) had a normal BMI, and 71.66 percent of them were multiparous. 69.17 percent of the population belonged to the middle class. Menorrhagia was the most common symptom (48.3%), followed by oligomenorrhoea (18.1%), and finally polymenorrhoea (13.3%). (17.27 percent ).

Conclusions: Excessive menstrual blood loss is a common reason for women seeking medical help, and it places a pressure on medical resources. According to our findings, most women with AUB were between the ages of 30 and 40, multiparous, and had a normal BMI, indicating that they were middle-class. The most prevalent symptom was menorrhagia. The clinical and epidemiologic trends of abnormal uterine bleeding in reproductive age groups are highlighted in the following study. This is a critical aspect of these patients' treatment. More research with big sample sizes and high levels of evidence should be undertaken to provide evidence of causation in order to forecast causality.

Author (S) Details

Neetu Singh

Department of Obstetrics and Gynecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Mariyam Faruqi

Department of Obstetrics and Gynecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Yashodhara Pradeep

Department of Obstetrics and Gynecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Shweta Bhatia

Department of Obstetrics and Gynecology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

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Histopathological Evaluation of Endometrial Tissue in Abnormal Uterine Bleeding: A Recent Study | Chapter 8 | Highlights on Medicine and Medical Science Vol. 17

 Background: Abnormal uterine bleeding can be caused by a number of conditions, and it is one of the most prevalent complaints that leads to endometrial sampling. It could be a natural physiological state, and just observation is necessary. Alternatively, the bleeding could be a symptom of a dangerous underlying illness that requires immediate attention.

Aim: To determine the varied patterns of endometrial curettings in abnormal uterine bleeding in different age groups and to evaluate the causes of abnormal uterine bleeding.

The research was carried out in the histopathology unit of the GMC Jammu Department of Pathology. All endometrial curettings and endometrial biopsy specimens obtained in the histology section were included in the study.

Results: Patients ranged in age from 14 to 75 years old. The age range 31-40 years had the highest number of cases in this study, with 188 cases (40.43 percent ). Secretory endometrium (170 instances) was the most prevalent pattern on histology, followed by proliferative endometrium (99 cases), endometrial hyperplasia (42 cases), and products of conception (27 cases). There were six cases of endometrial cancer and four occurrences of squamous cell carcinoma.

Conclusion: Endometrial tissue examined histopathologically in patients with atypical uterine bleeding reveals a wide range of alterations, ranging from normal endometrium during various hormonal cycles to cancer. As a result, it is a crucial diagnostic tool in the assessment of irregular uterine bleeding.

Author (S) Details

Ritu Bhagat
Demonstrator, Postgraduate Department of Pathology, GMC Jammu, India.

Chiterlekha Kundal
Demonstrator, Postgraduate Department of Pathology, GMC Jammu, India.

Subhash Bhardwaj
Demonstrator, Postgraduate Department of Pathology, GMC Jammu, India.

Vinod Kumar
Department of Medicine, GMC, Doda, India.

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Role of Uterine Conservative Surgery in Reproductive Age Group Women: A Retrospective Study | Chapter 6 | Highlights on Medicine and Medical Science Vol. 1

 Fibroids are a type of benign tumor that can cause severe dysmenorrhoea, bleeding, and infertility in reproductive-age women. Fibroids increase the chances of miscarriage, with submucosal and intramural fibroids having a higher probability of spontaneous abortion and a lower likelihood of live birth. As more women put off having children until their 30s or 40s, When fibroids become more symptomatic, uterine sparing treatment become increasingly necessary. Given the rising number of treatment options and changing care provider profiles, now is an excellent time to examine current practices and perspectives. Endoscopic myomectomy is the most popular minimally invasive surgical approach for treating different fibroids in individuals with AUB, with reproductive difficulties being the most typical example. 1) the prognosis of infertile patients following myomectomy 2) kind of uterine conservation surgery 3) the outcome of the technique used Materials and Procedures: This study comprised 130 women (aged 20 to 48) who came to Rajdeep endoscopy and IVF center in Kota with symptomatic fibroids and infertility. The highest proportion of myoma was reported in adults aged 20 to 40, and the most common fibroids were intramural 38.46 percent, according to our findings. The pregnancy rate has increased to 50-60% after both laparoscopy and abdominal myomectomy.

Conclusion: For women who want to preserve their uterus in their existing state, myomectomy is the most usual procedure. The operation is extremely safe when performed by a trained surgeon, with morbidity comparable to a hysterectomy.

Author (s) Details

Rajshree Gohaodkar
Rajdeep Nursing Home & Infertility Centre, India.

Deshdeepak
Rajdeep Nursing Home & Infertility Centre, India.

Shalini Gupta
Rajdeep Nursing Home & Infertility Centre, India.

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