Friday 12 November 2021

Determination of Hemodialysis Status in an Egyptian Coastal City, Alexandria: An Epidemiological Study with a 3-year Prospective Mortality Observation | Chapter 3 | Recent Developments in Medicine and Medical Research Vol. 8

 Background: In Egypt, hemodialysis (HD) is the most common form of RRT, and it is a significant financial burden on the health-care system. Many organisations, both governmental and non-governmental, have adopted HD since it is a crucial and lifesaving technique. In Egypt's Alexandria province, HD service is offered through fifty-seven HD units, twenty-one of which are nonprofit and thirty-six of which are private for-profit. Our goals were to investigate the epidemiology and estimate the three-year survival of ESRD patients treated with HD in Alexandria province's government facilities.

Design and Methods: The data of the patients was obtained in 2016 from all of the governmental hospitals in Alexandria province, which included seven HD units with a total of 687 patients. Demographic data, vascular access, HIV, HBV, and HCV serology, the potential aetiology of chronic kidney disease (CKD), related comorbidities, and regular laboratory variables were all included in a cross-sectional arm of the study. A three-year survival rate of the examined HD patients was also reported in a prospective phase of the trial.

The overall number of HD patients in Alexandria province in 2019 was 3552 in all HD units, resulting in an estimated HD prevalence rate of roughly 710 ppm. The 687 patients in the governmental HD facilities who were polled had a mean age of 50.78 years, with more males, and a mean duration of HD of 55 months. There was also no evidence of positive seroconversion to HCV, HBV, or HIV. Sixteen HCV antibody-positive individuals were treated with direct-acting antiviral medications and were subsequently PCR-negative for HCV. Males had a higher prevalence of HTN, while females had a higher prevalence of DM and combined DM and HTN. In about 37% of the HD patients evaluated, the goal haemoglobin level was present. The majority of the patients had serum calcium levels between 8 and 10 mg/dl, while 53% had serum phosphorus levels between 3-5.5 mg/dl. A para-thyroidectomy was performed in 2% of the instances investigated, whereas cinacalcet was used in 4% of the cases. The survival rates were 92.5 percent, 87 percent, and 82 percent after three, five, and seven years, respectively.

Conclusion: The epidemiology of hemodialysis patients in Alexandria province is similar to that of other Egyptian governorates in many ways, although no new epidemiology for the entire country has been published. After following the antiviral therapy approach, 11.2 percent of HCV Abs positive patients became PCR negative.

Author(S) Details

Abir Farouk Megahed
MOH Nephrology Administration, Mansoura Military Hospital, Department of Nephrology, Mansoura, Ministry of Health, Mansoura, Egypt.

Reem Mohamed Farouk Saleh
Alexandria University, Alexandria, Egypt.

Afaf Mohamed Fahmy
High Nurse and Supervisor on Nursing Staff in Hemodialysis in Alexandria, Egypt.

Nagy Sayed-Ahmed
Nephrology and Dialysis Unit (MNDU), Faculty of Medicine, Mansoura University, Mansoura, Egypt.

View Book:- https://stm.bookpi.org/RDMMR-V8/article/view/4562

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