We looked into whether thermal stimulation could help prevent atherosclerotic cardiovascular disease in the past (ASCVD). Variations in the expression of associated genes were validated in studies utilising human skeletal muscle-derived cells (SMDC). A small decrease in the number of cells was also verified. The application of thermal stimulation to cultured cells has long been connected with apoptosis. Although various research have confirmed the above, such as promoting apoptosis and decreasing apoptosis with heat stimulation, the precise effects of thermal stimulation on apoptosis have yet to be determined. In order to safely use heat stimulation for the prevention of ASCVD in vivo, we reexamined the effects of thermal stimulation on human skeletal muscle cells. We hypothesised that thermal stimulation of SMDC causes apoptosis based on our previous findings. This suggested that in order to prevent ASCVD in vivo, heat stimulation should be moderate.
Author(S) Details
Masayo Nagai
Department of Nursing Faculty of Health Science, Aino University, Japan.
Hidesuke Kaji
Division of Physiology and Metabolism, University of Hyogo, Division of Pathophysiology, Kobe Women’s University, Japan.
View Book:- https://stm.bookpi.org/RDMMR-V7/article/view/4535
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