Background: The most prominent contributions to left ventricular diastolic dysfunction (DD), left atrial remodelling, and atrial fibrillation are hypertension and left ventricular hypertrophy (LVH).
The major purpose of this study is to assess LA remodelling and left ventricular DD in individuals with and without paroxysmal atrial fibrillation (PAF) and essential hypertension (HTN).
Materials and Methods: A total of 128 patients with normal left ventricular systolic function participated in the study (LVEF50 percent ). They were split into two groups based on whether they had essential hypertension or not. The 65 normotensive people were divided into two groups: PAF (n=32) and no-PAF (n=33). PAF (n=32) and control no-PAF (n=31) hypertensive subjects were further divided into two groups.
In terms of gender, age, and weight, the patients in the control group were chosen to match the PAF groups. The patients were evaluated using a resting 12 lead ECG, 24 hour Holter ECG monitoring, 24 hour blood pressure monitoring, and 2D Doppler echocardiography. For three years, the follow-up was done every six months. The statistical analysis was performed using the MedCalc 12.3.0.0 statistics software for Windows.
The results were considered statistically significant when the p-value was less than 0.05.
PAF patients have bigger LA diameters as a result of their condition. Supplemental LA levels rise as a result of HTN. LA diameters are unaffected by the amount of PAF episodes. The gender of the patients has little impact on the statistical data, with PAF and HTN patients having bigger diameters.
Author (S) Details
Iosif Marincu
Department of Infectious Diseases, Pneumology and Parasitology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Methodological and Infectious Diseases Research Center, Romania.
Iulia Vidican
Department of Infectious Diseases, Pneumology and Parasitology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Methodological and Infectious Diseases Research Center, Romania.
Valentina Elena Avram
Department of Infectious Diseases, Pneumology and Parasitology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Methodological and Infectious Diseases Research Center, Romania.
Madalina Timircan
Department of Infectious Diseases, Pneumology and Parasitology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Methodological and Infectious Diseases Research Center, Romania.
Oana Suciu
Department of Infectious Diseases, Pneumology and Parasitology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Methodological and Infectious Diseases Research Center, Romania.
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