Central Retinal Vein Occlusion and Pseudoexfoliation Syndrome: A Brief Clinical Findings | Chapter 15 | New Horizons in Medicine and Medical Research Vol. 4

 The goal of this study is to see if there is a link between pseudoexfoliation syndrome (PXF) and the development of central retinal vascular occlusion (CRVO).

Methods: This was a retrospective, comparative investigation of the prevalence of pseudoexfoliation in three groups of patients: 48 patients with CRVO, 164 patients with BRVO, and 70 healthy volunteers (70 eyes). All of the patients were phakic and had never been diagnosed with glaucoma before. In terms of age and systemic hypertension, the patients were matched. At the time of presentation, all of the patients had normal intraocular pressure (IOP) (defined as less than or equal to 21 mmHg).

Results: PXF was detected in 14 of the 48 individuals in the CRVO group (29.17 percent ). PXF was found in 14 out of 164 patients in the BRVO group (8.5 percent), and six out of 70 patients in the control group (8.6 percent ). The percentage differences between the groups were calculated statistically.

noteworthy (P,0.001, X2 test). When we compared patient subgroups with ischemic CRVO to patient subgroups with non-ischemic CRVO, we discovered that in the ischemic CRVO group, 13 out of 27 patients (48.15 percent) were diagnosed with PXF, while one out of 21 patients in the non-ischemic CRVO group was diagnosed with PXF (4.7 percent ; P,0.001, X2 test). Patients with PXF had a 4.406 percent chance of getting CRVO compared to patients without PXF (confidence interval [CI], 2.03-9.54).

Conclusion: PXF and CRVO, particularly ischemia CRVO, are closely connected in our research. Because PXF is related with CRVO in the absence of glaucoma, our data imply that it may be an independent risk for CRVO.

Author(S) Details

Dimitrios Karagiannis
Ophthalmiatreio Eye hospital of Athens, Athens, Greece.

Georgios A. Kontadakis
Ophthalmiatreio Eye hospital of Athens, Athens, Greece and Department of Ophthalmology, University Hospital of Heraklion, University of Crete, Heraklion, Greece.

Nektarios E. Klados
Department of Ophthalmology, University Hospital of Heraklion, University of Crete, Heraklion, Greece.

Ioannis Tsoumpris
Ophthalmiatreio Eye hospital of Athens, Athens, Greece.

Artemios S. Kandarakis
Ophthalmiatreio Eye hospital of Athens, Athens, Greece.

Efstratios A. Parikakis
Ophthalmiatreio Eye hospital of Athens, Athens, Greece.

Ilias Georgalas
Department of Ophthalmology, General Hospital of Athens, Athens, Greece.

Miltiadis K. Tsilimbaris
Department of Ophthalmology, University Hospital of Heraklion, University of Crete, Heraklion, Greece.


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