PCOS (polycystic ovarian syndrome) is a prevalent endocrine disorder that affects women of reproductive age. The usual trifecta of PCOS symptoms is chronic anovulation, hyperandrogenism, and polycystic ovaries. Insulin resistance and metabolic disorders are among its biological features. In addition to its traditional roles in bone and calcium metabolism, vitamin D is now connected to insulin sensitivity, diabetes mellitus type 2 and gonadal activity. Vitamin D could be the missing piece in the puzzle of insulin resistance and PCOS.
Vitamin D levels in PCOS women are low, and vitamin D supplementation may help with the condition. However, clinical trials have not consistently supported this idea.
The connection between PCOS and vitamin D was investigated in a rural medical college in south India. 120 women with PCOS and 60 age-matched non-PCOS women had their BMI and vitamin D levels tested. In 60.8 percent of PCOS women and 61.7 percent of control women, vitamin D insufficiency was identified. Vitamin D levels are higher than 30 ng/ml in just 11.7 percent of the PCOS group and 13.3 percent of the control group. Vitamin D levels were 18.94, 19.2, and 18.6 ng/ml in 120 PCOS women, 68 non-obese PCOS women, and 52 obese PCOS women, respectively. Vitamin D levels are 18.4, 19.0, and 17.3 ng/ml in 60 non-PCOS women, 39 non-PCOS non-obesity women, and 21 non-PCOS obese women, respectively. These differences aren't significant statistically. As a result, it is determined that vitamin insufficiency is prevalent in the general population and has no bearing on PCOS or BMI.Author(S) Details
Alla Satyanarayana Reddy
Vinayaka Mission`s Research Foundation (DU), Karaikal, Pondicherry, India.
G. Ambujam
Vinayaka Mission`s Research Foundation (DU), Karaikal, Pondicherry, India.
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