Detection of HBV DNA in HBsAg Negative Patients | Chapter 4 | New Advances in Medicine and Medical Science Vol. 3

 The term "Occult Hepatitis B Infection" (OBI) refers to the steadfastness of hepatitis B viral DNA (HBV DNA) hereditary or liver in the absence of perceptible HBsAg. When it comes to halting HBV transmission in our society, this has become a potential danger. The aim of this study search out identify the HBV genotype(s) connected to OBI in Ibadan, Nigeria, as well as the predominance of the infection. A total of 219 ancestry samples were included in this place study that were previously proven negative for HBsAg using ELISA forms. The HBV DNA in the samples was detected utilizing a nested polymerase chemical reaction.Using descriptive enumerations and the Chi square with a p-worth of 0.05, the data was analysed. There were 102 (46.6% of fellows) and 117 (53.4% of women) players overall (P = 0.204). The participants' ages range from 1 to 70, accompanying the mean age for females being 32.1 age (SD: 12.7) and for men being 33.9 age (SD: 12.4). Participants' clinical environments ranged from those the one were asymptomatic to those who had severe hepatitis disease. A predominance of 0.5% for HBV DNA was found in individual of the 219 samples analysed. The positive sample arose a 30-year-traditional female. Due to inadequate series data, we were sidelined to identify the genotype of the confine. The prevalence of 0.5% OBI in the study provides evidence of mysterious hepatitis B viral distribution in our community. To prevent the spread of the bug through the transfusion of polluted ancestry and blood fruit, blood wholes must be screened utilizing the Nucleic Acid Testing (NAT) technique. Increasing public knowledge of HBV vaccination is likewise necessary to decrease the risk that OBI may present.

Author(s) Details:

Akinbobola Ayokunle Adeniyi,
Department of Medical Microbiology and Parasitology, University College Hospital, Nigeria.

Priscilla O. Olamiju,
Jefferson’s Avenue Gaylord, USA.

Olubunmi Aanu Adeniyi,
Association for Reproductive and Family Health (ARFH), Ibadan, Nigeria.

Stephen Oluwasegun Adetunji,
Department of Microbiology and Infection Services, University Hospitals Sussex, United Kingdom.

Olalekan Ademola Kemiki,
Molecular and Tissue Culture Laboratory, BABCOCK, Nigeria.

Georgina N. Odaibo,
Virology Department, University of Ibadan, Nigeria.

Please see the link here: https://stm.bookpi.org/NAMMS-V3/article/view/10770