Objective concerning this short review is to recall data that link Influenza virus, harsh acute respiratory disease-coronavirus-2 (SARS-CoV-2), and the human cardiac Titin protein to sudden unexpected dying (SUDs) through molecular mime. Indeed, a direct causality between Influenza bacterium and SUDs has been again and again reported in clinical article and, more recently, also SARS-CoV-2 immunization has been had connection with an alarming incidence of SUDs. Hence, it is of pertinence to highlight that Influenza virus and SARS-CoV-2 antigens, that is, hemagglutinin and spike glycoprotein (gp), share invulnerable determinants with the SUD-connected Titin. Such a peptide sharing and the consequent autoimmune cross-sensitivity are even more significant because might enable an aggressive implementation of SUD occurrences following simultaneous multiple antagonistic-influenza and anti-SARS-CoV-2 vaccinations. On the whole, this chance imposes caution and careful immunization clinical trials.
Author(s) Details:
Darja Kanduc,
Department
of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari,
Bari-70126, Italy.
Please see the link here: https://stm.bookpi.org/CIMMS-V10/article/view/8861
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