Phenytoin is a usually used anticonvulsant drug in children and persons for tonic clonic and biased seizures with common aftereffects like nausea, stomach pain, loss of appetite, wax hypertrophy etc. We encountered a patient 34-year-traditional male who bestowed with history of individual episode of convulsion, for that he was prescribed Tab Phenytoin 100mg double daily by oral route. After 15 days he grown rash over trunk which contaminate the whole carcass in two days associated with itching and climbing. There was no familial or personal history of drug aversion or skin conditions. Physical examination revealed diversified, purpuric macules and papules mainly on the body with scaling. Patient was acknowledged and subjected to investigations, that showed common report. Tab Phenytoin was withdrawn and Tab Prednisolone 40mg orally day-to-day was given and tapered by 10mg already in 15 days during that the lesions slowly showed bettering. Symptoms resolved completely in 2 weeks following in position or time phenytoin withdrawal and no adverse follow-up reported. Thus the same case presentation exhibits a rare antagonistic effect of phenytoin on skin.
Author(s) Details:
S. Suma,
Saveetha
Medical College and Hospital, Chennai, Tamil Nadu, India.
K.
Tejashwini,
Cognizant
Technology Solutions, Mysore, Karnataka, India.
V. Hari Prasad,
Department of Forensic Medicine, Panimalar Medical College and
Hospital, Chennai, India.
Please see the link here: https://stm.bookpi.org/CIMMS-V10/article/view/8868
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