Tuesday, 20 December 2022

Determining the Association of Mean Platelet Volume in the Late First Trimester of Pregnancy and Development of Preeclampsia| Chapter 3 | Current Innovations in Medicine and Medical Science Vol. 10

 The present study proposed to find out the correlation betwixt the mean platelet volume in the late 1st trimester of gestation and development of a Preeclampsia later on. Preeclampsia (PE) is a gestation-specific healing disorder that is characterized by incitement of the coagulation plan, and endothelial cell dysfunction. This disorder is a major cause of motherly and fetal depression and mortality.It was a prospective companion study in which 500 significant women (11–14 weeks of gestation) were registered and their mean platelet volume (MPV) was calculated. They were followed till delivery. MPV of pre-eclamptic and normotensive wives was compared.MPV of pre-eclamptic daughters was significantly higher than that of the normotensive wives (p = 0.001).MPV > 10.55 fL was found to be 68.7% delicate and 55.9% specific for the prophecy of Preeclampsia with a negative predictive profit of 87.6%. Thestudy suggest attending future research with a large sample amount to investigate the blend of mean platelet volume with added cost-effective indicators in order to increase the sensitivity and particularity of preeclampsia prediction outside adding additional fiscal burden to expectant inventors, particularly in low-means settings.

Author(s) Details:

Shailja S. Bhamri,
Department of Obstetrics and Gynecology, King George Medical University, Lucknow, Uttar Pradesh, India.

Urmila Singh,
Department of Obstetrics and Gynecology, King George Medical University, Lucknow, Uttar Pradesh, India.

Seema Mehrotra,
Department of Obstetrics and Gynecology, King George Medical University, Lucknow, Uttar Pradesh, India.

Vandana Solanki,
Department of Obstetrics and Gynecology, King George Medical University, Lucknow, Uttar Pradesh, India.

Please see the link here: https://stm.bookpi.org/CIMMS-V10/article/view/8863

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