Monday, 22 November 2021

Study about Homocysteine: A Biomarker in Neurodegenerative Diseases | Chapter 10 | Issues and Development in Health Research Vol. 7

 Homocysteine (Hcy) levels in Indians are greater than in Europeans. Hyperhomocysteinemia (HHcy) is an early risk factor for stroke, MI, and other vascular illnesses that is distinct, powerful, graded, and easily quantifiable. A vitamin deficiency or an inherited trait could be the cause. Vitamin B12, Vitamin B6, and folic acid, all of which are required for methionine metabolism, are in short supply in the majority of vegetarian Indians. A dose-dependent connection between mild to moderate increases in plasma Hcy and the risk of neurodegenerative diseases has been established in epidemiological research. Hcy is a neurotoxic substance that serves as a proxy for vitamin insufficiency. Patients with a high Hcy levels have a higher risk of atherosclerotic events. Hyperhomocysteinemia is a common problem among the elderly. According to the findings of this investigation, Hcy levels are higher in patients with neurologic diseases. Both male and female people have statistically significant Hcy levels. Hcy levels are higher in males with neurological disorders. The availability of vitamin-fortified meals, particularly cereals, can help to avoid or delay the onset of age-related neurological disorders in hyperhomocystemic high-risk patients.


Author(S) Details

N. Jayanthi Bai
Department of Laboratory Medicine, SK Hospital, Edappazhinji, Thiruvananthapuram 695006-India.

S. Jayakrishnan
Department of Laboratory Medicine, SK Hospital, Edappazhinji, Thiruvananthapuram 695006-India.

View Book:- https://stm.bookpi.org/IDHR-V7/article/view/4813

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