Wednesday 13 January 2021

Screening of the Antimicrobial Activity of Leaf Extracts from Different Plant Families (Boraginaceae, Fabaceae, Lamiaceae, and Lauraceae) against Microorganisms of Clinical Importance | Chapter 6 | Trends in Pharmaceutical Research and Development Vol. 6

 As they possess natural products, including secondary metabolites and their derivatives, conventional medicinal plants serve as potential sources of new antimicrobial agents. Objectives: The antimicrobial activities of Sassafras albidum (Nutt.), Ehretia anacua (Terán & Berl.), Melissa officinalis (Linn.), Eysenhardtia texana (Scheele), and Melissa odorata were investigated in this review. Specifically, this research aims to assess the antimicrobial ability of different leaf extracts and to qualitatively determine the existence of secondary metabolites. Place and Period of Study: The San Antonio Botanical Garden in Texas has collected plant leaves. Microbial experiments and chemical analysis were conducted at the Texas A&M International University, Laredo Texas Department of Biology and Chemistry. From October 2013 to May 2016, this study was completed. Methodology: Leaves were collected and leaf extracts were prepared from aqueous, acetone, diethyl ether and ethanol. Using disc diffusion assays, antimicrobial activity against bacteria and fungi was examined. In order to qualitatively classify secondary metabolites, phytochemical screening was carried out. Results and Conclusion: Diethyl E and ethanol. A statistically important antimicrobial activity against S was demonstrated by anacua (Boraginaceae) extracts. From aureus. Although the 7.4 mm and 7.5 mm values for ethanol and diethyl ether extracts may be poor for the inhibition region, the potential for E. For Anti-S. Anacua. The operation of the aureus cannot be undermined. The observable presence of alkaloids, diterpenes and phenols in ethanol and diethyl E was demonstrated by phytochemical analysis. Extracts from Anacua. While preliminary, the results of this study showed the potential of E. Anacua as a new bioactive metabolite source. Ethanol E was demonstrated by phytochemical research. Anacua extract was positive for alkaloids, diterpenes, cardiac glycosides, and phenols, whereas diethyl ether E was positive. Anacua extract was positive for alkaloids, phenols, and diterpenes. This is the first article relating to E. The antimicrobial activity of anacua and the secondary metabolites thereof. Alkaloids, diterpenes, and phenols are possibly responsible for the antimicrobial activity observed, either individually or synergistically. In order to precisely define, quantify and isolate the bioactive compounds that could work against S, further investigations are required. Skin infection associated with aureus.

Author (s) Details

Ruby A. Ynalvez
Department of Biology and Chemistry, Texas A&M International University, USA.

Kassandra L. Compean
Department of Biology and Chemistry, Texas A&M International University, USA.

Alfred Addo-Mensah
Department of Biology and Chemistry, Texas A&M International University, USA.

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