Background: Phyllodes tumours are rare fibroepithelial lesions of the breast. The words “phyllodes” are derived from the latin phyllodium and greek phullodes meaning leaf like. Unlike carcinoma breast, phyllodes tumors start outside of the ducts and lobules, in the breast’s connective tissue, called the stroma which includes the fatty tissue and ligaments that surround the ducts, lobules, and blood and lymph vessels in the breast.
Aim: The aim of the study is to clinical presentation and
management of phyllodes tumour.
Methods: A prospective study was conducted in the department of
surgery in a medical college and hospital in central India over a period from
March 2006 to March 2016. A total of 96 female patients of phyllodes tumour
were included in this study. A detailed clinical history and examination of the
breast lump were done.
Results: Out of 98 patients, the majority of patients were in the
age group of 31 - 40 years. The mean age of presentation was 37 years ranging
from 12 years to 57 years. 43.75% of patients had breast lumps involving all
four quadrants of the breast. All patients were subjected to surgical
management. The modality of treatment available for surgical management of
phyllodes tumor includes wide local excision, lumpectomy, simple mastectomy and
radical mastectomy. The surgical management includes wide local excision in 28,
lumpectomy in 26, simple mastectomy in 40 and radical mastectomy in 02
patients. Three histotypes of phyllodes tumor, i.e., benign (42 cases, 43.75%),
borderline (12 cases, 12.5%), and malignant (42 cases, 43.75%) were observed in
the present study. The adjuvant radiotherapy may be effective in reducing the
risk of local recurrence. Three drugs such as ifosfamide, cisplatin and
etoposide have been described to be effective for malignant phyllodes.
Conclusions: Preoperative diagnosis and proper management are
crucial in phyllodes tumours because of their tendency to recur and malignant
potential in some of these tumours. Excision of the phyllodes tumour with a
wide margin of healthy tissue is a safe and effective method of local control.
A positive axillary lymph node enlargement would necessitate an axillary lymph
node dissection followed by chemotherapy and radiotherapy.
Author
(s) Details
Ashok Suryabhanji
Gajbhiye
Department of Surgery, IGGMC, NAGPUR-18, Maharashtra, India.
Saiesha Nagavarapu
Department of Government Medical College, Chandrapur, India.
Ambrish Somkuwar
Department of Surgery, IGGMC, NAGPUR-18, Maharashtra, India.
Avinash Bokde
Department of Surgery, IGGMC, NAGPUR-18, Maharashtra, India.
Vaibhav Nasare
Department of Surgery, IGGMC, NAGPUR-18, Maharashtra, India.
Kishor Jehughale
Department of Surgery, IGGMC, NAGPUR-18, Maharashtra, India.
Ankit Agrawal
Department of Surgery, IGGMC, NAGPUR-18, Maharashtra, India.
Please see the book here:- https://doi.org/10.9734/bpi/msti/v7/3067
