Gestational Diabetes Mellitus and Diabetes in Pregnancy as Risk Factors for Preterm Premature Rupture of Membranes | Chapter 6 | Medical Science: Updates and Prospects Vol. 7

 

Premature rupture of membranes is the rupture of gestational membranes prior to the onset of labour. When membrane rupture occurs before 37 weeks of gestation, it is referred to as preterm premature rupture of membrane, which is a significant risk factor for perinatal morbidity and mortality. Gestational diabetes mellitus and diabetes in pregnancy probably increase the risk of premature rupture of membranes or the prevalence of premature rupture of membranes and fetal complications during pregnancy. The objective of this descriptive cross-sectional study was to analyse the frequency of patients with Gestational Diabetes Mellitus (GDM) and Diabetes mellitus in Pregnancy (DIP) among all admitted PPROM patients in the Fetomaternal Medicine unit of Dhaka Medical College Hospital from 01/01/2020 to 31/12/2020. A total of 103 patients with PPROM were included. Among them, 10 (9.7%) participants were suffering from gestational diabetes mellitus and diabetes in pregnancy, 6 (5.8%) were multiple gestation, 7 (6.7%) were associated with preterm labor, 7 (6.79%) patients had gestational hypertension, 4 (3.88%) were with fetal growth restriction, 3 (2.91%) had fetus with congenital anomaly and 2(1.94%) patients were with anaemia. The study found that GDM and DIP were the most common risk factors among PPROM patients in this cohort. As still now there is scarcity of study regarding the identification of risk factors of PPROM; more studies with a large sample size are needed. Larger studies are recommended to further establish the role of GDM and DIP in its pathogenesis. Awareness should be developed among obstetricians towards early detection of GDM and DIP as a preventive method for PPROM from the first trimester of pregnancy.

 

Author(s) Details

Ummae Tania Nasrin
Shaheed Ahsan Ullah Master General Hospital, Tongi, Bangladesh.

 

Tajmira Sultana
Fetomaternal Medicine Unit, Dhaka Medical College Hospital, Bangladesh.

 

Mohammad Rafiqul Kabir
Sheikh Sayra Khatun Medical College, Gopalgonj, Bangladesh.

 

Azmary Momtaz
Department of Pharmacology, Delta Medical College, Dhaka, Bangladesh.

 

Hafiza Farzana
Fetomaternal Medicine Unit, Dhaka Medical College Hospital, Bangladesh.

 

Bappi Das
Fetomaternal Medicine Unit, Dhaka Medical College Hospital, Bangladesh.

 

Please see the book here :- https://doi.org/10.9734/bpi/msup/v7/7156