Background: Urinary electrolytes play a key role in
assessing hydration status, metabolism and renal function. The term “urinary
electrolytes” generally refers to the urinary concentrations of sodium,
potassium, and chloride. In many parts of the world, particularly in
sub-Saharan Africa, data on the composition and concentration of urinary electrolytes
remain limited, especially in rural areas.
Aims: This study aimed to characterise and quantify the
major urinary electrolytes (Na⁺, K⁺, Ca²⁺, Cl⁻) in two rural areas of southern
Chad: Grand Sido and Kouh-Est.
Methods: A cross-sectional, descriptive, and analytical
study was conducted among 783 volunteer participants aged 5–90 years residing
in Grand Sido (n = 430) and Kouh-Est (n = 353). Morning urine samples were
collected under aseptic conditions and transported to the laboratory in
accordance with storage conditions. Urinary concentrations of sodium (Na⁺),
potassium (K⁺), calcium (Ca²⁺), and chloride (Cl⁻) were determined using
standardised biochemical methods (colourimetric methods). Statistical analyses
were performed using the chi-square test to compare electrolyte profiles
between the two areas and across age groups, with a significance threshold set
at p < 0.05.
Findings: This study highlights significant differences in
urinary electrolyte profiles between Grand Sido and Kouh-Est, reflecting the
influence of nutritional factors, access to drinking water, and local
environmental conditions. The observed prevalence of electrolyte imbalances,
particularly hyponatraemia and hypocalcaemia, suggests a state of nutritional
and metabolic vulnerability within the studied populations. These disturbances
may be associated with inadequate dietary intake, increased hydroelectrolytic
losses, or the presence of chronic and endemic parasitic diseases, including
renal disorders and schistosomiasis.
Conclusion: These findings provide a useful reference for
assessing hydration status and renal function in these rural populations. They
also offer an important basis for developing targeted nutrition, prevention,
and public health strategies adapted to the specific context of southern Chad.
Despite certain limitations, including the absence of systematic measurement of
urinary creatinine and acid–base parameters and limited information on
participants’ dietary habits, this study provides important preliminary data
and a regional baseline that may guide future research in southern Chad.
Author(s) Details
Abdelsalam Hassan
Gogo
Laboratoire d’expertise, de Diagnostic et de Recherche (LaboRedes), Faculté
des Sciences de la Santé Humaine, Université de N'Djamena, BP 1117, Chad.
Mahamat Alhadj Moussa
Ibrahim
Laboratoire d’expertise, de Diagnostic et de Recherche (LaboRedes), Faculté
des Sciences de la Santé Humaine, Université de N'Djamena, BP 1117, Chad.
Brahim Adoum Ahmat
Laboratoire d’expertise, de Diagnostic et de Recherche (LaboRedes), Faculté
des Sciences de la Santé Humaine, Université de N'Djamena, BP 1117, Chad.
Abdelsalam Tidjani
Laboratoire d’expertise, de Diagnostic et de Recherche (LaboRedes), Faculté
des Sciences de la Santé Humaine, Université de N'Djamena, BP 1117, Chad.
Aly Savadogo
Laboratoire de Biochimie et Immunologie Appliquées (LaBIA), Université
Joseph KI-Zerbo, BP 7131 Ouagadougou
03, Burkina Faso.
Please see the book here :- https://doi.org/10.9734/bpi/nhstc/v9/7285
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