Gestational Diabetes Mellitus and Diabetes in Pregnancy as Risk Factors for Preterm Premature Rupture of Membranes | Chapter 6 | Medical Science: Updates and Prospects Vol. 7

 

Premature rupture of membranes is the rupture of gestational membranes prior to the onset of labour. When membrane rupture occurs before 37 weeks of gestation, it is referred to as preterm premature rupture of membrane, which is a significant risk factor for perinatal morbidity and mortality. Gestational diabetes mellitus and diabetes in pregnancy probably increase the risk of premature rupture of membranes or the prevalence of premature rupture of membranes and fetal complications during pregnancy. The objective of this descriptive cross-sectional study was to analyse the frequency of patients with Gestational Diabetes Mellitus (GDM) and Diabetes mellitus in Pregnancy (DIP) among all admitted PPROM patients in the Fetomaternal Medicine unit of Dhaka Medical College Hospital from 01/01/2020 to 31/12/2020. A total of 103 patients with PPROM were included. Among them, 10 (9.7%) participants were suffering from gestational diabetes mellitus and diabetes in pregnancy, 6 (5.8%) were multiple gestation, 7 (6.7%) were associated with preterm labor, 7 (6.79%) patients had gestational hypertension, 4 (3.88%) were with fetal growth restriction, 3 (2.91%) had fetus with congenital anomaly and 2(1.94%) patients were with anaemia. The study found that GDM and DIP were the most common risk factors among PPROM patients in this cohort. As still now there is scarcity of study regarding the identification of risk factors of PPROM; more studies with a large sample size are needed. Larger studies are recommended to further establish the role of GDM and DIP in its pathogenesis. Awareness should be developed among obstetricians towards early detection of GDM and DIP as a preventive method for PPROM from the first trimester of pregnancy.

 

Author(s) Details

Ummae Tania Nasrin
Shaheed Ahsan Ullah Master General Hospital, Tongi, Bangladesh.

 

Tajmira Sultana
Fetomaternal Medicine Unit, Dhaka Medical College Hospital, Bangladesh.

 

Mohammad Rafiqul Kabir
Sheikh Sayra Khatun Medical College, Gopalgonj, Bangladesh.

 

Azmary Momtaz
Department of Pharmacology, Delta Medical College, Dhaka, Bangladesh.

 

Hafiza Farzana
Fetomaternal Medicine Unit, Dhaka Medical College Hospital, Bangladesh.

 

Bappi Das
Fetomaternal Medicine Unit, Dhaka Medical College Hospital, Bangladesh.

 

Please see the book here :- https://doi.org/10.9734/bpi/msup/v7/7156

Women and Pregnancies as an Immediate Target against the Obesity Epidemic | Chapter 14 | Advancement and New Understanding in Medical Science Vol. 1

People with obesity worldwide have become a major challenge in this 21st century with an apparent irresistible rise of this epidemic since the 1970’s. Nowadays, it is evaluated that obese people (≥ 30 kg/m²) represent some one billion inhabitants (out of seven) on this planet. The author wishes to enlarge an important current debate among obstetricians trying to sensitize specialists of obesity/endocrinology/ nutrition, and make them aware of a possible very important debate: having a “normal shaped” baby (neither too small, nor too big, 10% of SGA, small for gestational age and 10% of LGA, large for gestational age), is possible by an optimal gestational weight gain (optGWG) during pregnancy. This is a simple- mathematical linear equation, y= ax+b (y being optimal gestational weight gain, optGWG, x being pre-pregnancy body mass index, ppBMI). Beginning with severe obesity (36 kg/m²), women should not gain weight during their pregnancy, while they should lose weight in higher BMIs (e.g., losing 6 kg for a 40 kg/m² morbid obese). This is predictable since the first trimester of pregnancy. This chapter concluded that besides actively counter balancing morbid effects of high BMIs in pregnancies (and, importantly for the future of mankind, by avoiding a lot of macrosomic and LGA newborns), should imply new habits in women’s future lives afterwards.

Author(s) Details:

Pierre-Yves Robillard,
Service de Néonatologie, Centre Hospitalier Universitaire Sud Réunion, BP 350, 97448 Saint-Pierre Cedex, La Réunion, France and Centre d’Etudes Périnatales Océan Indien (CEPOI), Centre Hospitalier Universitaire Sud Réunion, BP 350, 97448 Saint-Pierre Cedex, La Réunion, France.

Please see the link here: https://stm.bookpi.org/ANUMS-V1/article/view/13031

Gestational Care an Opportunity to Prevent NCDs in Future Generations| Chapter 3 | Perspective of Recent Advances in Medical Research Vol. 3

 In the case of diabetes, the intrauterine atmosphere significantly contributes to corpulence and diabetes epi­demics. The population accompanying an increased prevalence of diabetes will steadily be disproportionately troubled by the epidemics, which leads to a enduring broadening of health differences among racial and cultural groups. Understanding the transgenerational epidemiology and plant structure of diabetes is essential; developing simple, economical, and efficient stop strategies is vital. Performing up-to-date screening of meaningful women for glucose bigotry, attaining euglycemia, and ratifying appropriate nutrition n may counter all of the probabilities (i.e., the endless loop of transmission of glucose bigotry from one production to another). It is required to “Focus on the Fetus for the Future” to contain the epidemic of diabetes. To prevent noncommunicable ailments, GDM provides a meaningful opportunity for developing, experiment, and implementing dispassionate strategies.

Author(s) Details:

Rajesh Jain,
Community Medicine, Rama Medical College Hospital & Research Centre, Kanpur, India.

Anju Gahlot,
Community Medicine, Rama Medical College Hospital & Research Centre, Kanpur, India.

Chitra Rani Chauhan,
Community Medicine, Rama Medical College Hospital & Research Centre, Kanpur, India.

N. Bhavatharini,
SRC Diabetes Centre, Erode, Tamil Nadu, India.

V Seshiah,
Hony Distinguished Professor of The Tamil Nadu Dr. M.G.R Medical University, Tamil Nadu, India.

Please see the link here: https://stm.bookpi.org/PRAMR-V3/article/view/9061

A Detailed Morphology and Histological Study of Placenta in Normal and Diabetic Pregnancies | Chapter 5 | Highlights on Medicine and Medical Science Vol. 17

 Introduction: Many physiological alterations that enhance insulin resistance are generated by pregnancy in a diabetogenic situation. The placenta is a vital organ for the developing foetus, as well as the human body's most accessible organ. Glucose tolerance has decreased by the third trimester of a typical pregnancy, although insulin levels in the blood have grown.

Aim: To determine the pregnancy's outcome, the placenta of a normal pregnancy is compared to the placenta of a diabetic pregnancy.

The current investigation used 50 placenta specimens with intact umbilical cords acquired from the Department of Obstetrics and Gynecology as part of a case-control study.

The shape and weight of the placenta varied slightly. The control group's mean placenta weight was 452.80 grammes, with a standard deviation of 140.93 grammes, while the case group's mean placenta weight was 406.00 grammes, with a standard deviation of 210.31 grammes. The mother's random blood sugar was substantially higher in the control group than in the cases (t=2.91, p0.01).

According to the current study, there was a tendency for placental weight and new-born weight to increase in complex pregnancies when compared to normal pregnancies. This showed an earlier diagnosis and adherence to the treatment strategy in diabetes pregnancies.

Author (S) Details

Durgesh Singh
Department of Anatomy, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Shashi Prabha Singh
Department of Biochemistry, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Priti Sinha
Department of Anatomy, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Neha Gupta
Department of Anatomy, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

Rakesh Sharma
Department of Biochemistry, Shaikh-ul-Hind Maulana Mahmood Hasan (Government) Medical College, Saharanpur, Uttar Pradesh, India.

View Book :- https://stm.bookpi.org/HMMS-V17/article/view/2608