The Autonomic, Hormonal, and Immunological Contributions to the Metabolism and Control of Adipose Tissue as an Organ | Chapter 11 | Emerging Trends in Disease and Health Research Vol. 5

 White adipose tissue (WAT) has traditionally been thought of as a passive storage deposit of surplus lipid as an energy reserve. Recent research, however, reveals that WAT functions as an organ system, interacting with the autonomic neural, endocrine, and immune systems. As a result, WAT may operate as a regulatory organ that aids in the maintenance of homeostasis in the body. This cross-sectional study analyses physiological data from 30 patients at the Pinewood Natural Health Centre in Toronto, Canada, to describe the role of WAT in homeostasis mediation. Statistical methods generate a formula that describes the dynamic congruence, which adds to an understanding of the organism through systems medicine (SM). Multiple variables were examined and associated using multiple regression analysis, including body metrics, body composition, metabolic parameters, heart rate variability, and the immunological, autonomous, neurological, and endocrine systems. The null hypothesis stated that no variables would correlate; the alternative hypothesis stated that at least two variables would correlate to indicate congruence and order. The current study aimed to see if different markers of endocrine, metabolic, anthropometric, and immunological functioning linked with evidence supporting the WAT as a contributor to homeostasis. The findings of this investigation revealed high relationships with immune system and metabolism markers, but just a few with the autonomous nervous system. This implies that, despite the body's complexity, not all systems contribute equally heavily to general homeostasis, but that the WAT mass plays an important role in sustaining homeostasis.

Author(S) Details

Michael S. Rahman
Division of Biomedical Sciences, Colleges of Medicine and Graduate Studies, University of Science Arts and Technology, Montserrat, BWI, USA.

George P. Einstein
Einstein Medical Institute, North Palm Beach, USA.

Orien L. Tulp
Pinewood Natural Health Centre, Ontario, Canada.

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