Mean Epidermal Thickness from Different Regions of Skin of Human Fetuses of 11-40 Weeks of Gestational Age: A Histometric Study | Chapter 4 | New Frontiers in Medicine and Medical Research Vol. 4

 Background: Determining foetal epidermal thickness is important for dermatological study and foetal preterm diagnosis.

The goal of this study was to obtain baseline data on foetal epidermal thickness and, secondarily, to investigate the relationship between GA and epidermal thickness.

Materials and Procedures: Thirty foetuses, ranging in age from 11 to 40 weeks, were chosen for the study. At a four-week interval, they were divided into six groups. The average epidermal thickness was assessed on the belly, interscapular area, scalp, and palm, among other places. The amscope 5MP Aptina MT9P001 was used to do the histometric study.

The average gestational age was 25.67 x 8.45 weeks. The abdominal, interscapular, scalp, and palmar epidermal thicknesses were 21.9 12.9 m (3.41–42.48), 111.21 74.39 m (7.9–214.51), 27.58 13.26 m (11.7–46.2), and 139.73 96.40 m (7.3–280.51), respectively. Based on the ANOVA (P = 1.98E 13 P 0.05 significant) and paired t test of interregional comparison, the epidermal growth pattern of the different regions was significantly different.

Conclusions: There is a substantial positive association between epidermal thickness and GA and anatomical sites. We underline the importance of epidermal thickness as a newborn maturity indicator.

Author (S) Details

Shivani Dhingra
Dr. Ram Manohar Lohia Institute of Medical Sciences, Gomti Nagar, Lucknow, Uttar Pradesh, India.

Adil Asghar
All India Institute of Medial Sciences, Patna, Bihar, India.

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