The thyroid gland is the body's main
metabolic regulator. Normal organ development necessitates thyroid hormones.
Thyroid hormones in high doses have been shown to change oxygen metabolism in
cells and accelerate the formation of free radicals. When compared to normal
and hypothyroidism, thyroid hormone has a pro-oxidant action and increases the
generation of oxygen free radicals, resulting in a drop in antioxidant status
in hyperthyroidism. Oxidative stress is also caused by thyroxin administration.
Oxidative stress and hypothyroidism both impair the immune system. The thyroid
gland appears to play a key role in the generation of widespread oxidative
stress in pathological states. Thyroid hormones are essential regulators of
mitochondrial oxidative metabolism. The goal of this research is to examine at free
radical scavenging activity, lipid peroxidation, and other related topics. and
antioxidant levels in hyperthyroidism and hypothyroidism patients In
conclusion, our findings imply that individuals with hypothyroidism and
hyperthyroidism have a high generation of ROS and oxidative stress, as well as
increased lipid peroxidation and a failure of antioxidant defence mechanisms.
Author(s) Details
Department of Biochemistry, Kongunadu Arts and Science College, G. N. Mills, Coimbatore, Tamil Nadu, India.
Indira A. Jayaraaj
Department of Biochemistry, Kongunadu Arts and Science College, G. N. Mills, Coimbatore, Tamil Nadu, India.
Jeganathan Prabhakar
J. P. Thyroid Clinic, Coimbatore, Tamilnadu, India.
View Book :- https://stm.bookpi.org/HMMR-V12/article/view/1379
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