Acne vulgaris is one of the most common dermatological
disorders, affecting approximately 80–85% of adolescents and young adults
worldwide. Major complications of acne include scarring as well as psychosocial
distress, which can persist long after the active lesions have resolved. Its
onset in adolescence may add to the emotional and psychological challenges
experienced during this developmental stage, potentially affecting body image,
socialisation, and sexuality. Platelet-rich plasma (PRP) has emerged as a
valuable tool in the management of acne scars, offering a safe, autologous, and
minimally invasive option that harnesses the body’s regenerative potential. Its
efficacy is most evident when used in combination with procedures such as
microneedling, fractional CO₂ laser, and subcision. By promoting collagen
remodelling, angiogenesis, and epidermal regeneration, PRP addresses the core
pathophysiology of scarring.
However, the lack of standardised preparation protocols,
variability in outcomes, and limited large-scale randomised trials remain
challenges. Future advances in biologically enhanced PRP formulations,
integration with regenerative medicine, and development of standardised
guidelines are likely to strengthen its role in aesthetic dermatology. For now,
PRP represents a promising adjunctive modality that bridges the gap between
conventional procedures and next-generation regenerative therapies for acne
scars. This review briefly discusses the role of PRP in the management of acne
scars.
Author(s) Details
Sweta S Kumar
Department of Dermatology, UPUMS Saifai, India.
Monika Srivastava
Department of Anatomy, UPUMS Saifai, India.
Nisha Yadav
Department of Anatomy, UPUMS Saifai, India.
Sanjay Kannaujia
Department of Pathology, UPUMS Saifai, India.
Santosh Kumar
Department of Respiratory Medicine, ASMC Etah, India.
Utkarsh Tripathi
Department of Dermatology, UPUMS Saifai, India.
Please see the book here :- https://doi.org/10.9734/bpi/msraa/v12/6259
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