Intra-Arterial Therapy with 90Y for Hepatic Tumour Lesions: A Review | Chapter 5 | Medical Science: Recent Advances and Applications Vol. 12

 

Aim: The objective of this integrative review study was to identify existing studies in the literature that provide information on the advances associated with the therapeutic technique of radioembolization with 90Y-labelled microspheres and its relationship within radiology, from the perspective of expanding the culture of radiological protection.

 

Methodology: Through an integrative literature review, the advances associated with the therapeutic technique of radioembolization with yttrium-90 (90Y) microspheres were analysed, highlighting the reduction of radiation dose in medical and occupational exposures, as well as evaluating the role of intra-arterial radionuclides in terms of survival benefit, progression-free survival, and quality of life.

 

Results: The results showed that therapeutic association with radioembolization using 90Y microspheres was effective in the treatment of liver tumours, but further studies are still required to determine ideal administration protocols and combination with radionuclide therapy.

 

Conclusion: Moreover, additional research is needed to establish the absorbed dose delivered to the tumour, taking into account its specific radiosensitivity and the desired final mass of the treated lesion.

 

 

Author(s) Details

Adrine Silveira da Silva
Universidade Franciscana - UFN, 97010-032, Santa Maria, RS, Brazil.

 

Luísa Vargas Cassol
Universidade Franciscana - UFN, 97010-032, Santa Maria, RS, Brazil.

 

Cássio Mori da Silva
Universidade Franciscana - UFN, 97010-032, Santa Maria, RS, Brazil.

 

Jéssica Fetzer da Costa Rosa
Universidade Franciscana - UFN, 97010-032, Santa Maria, RS, Brazil.

 

Vagner Bolzan
Instituto Federal de Santa Catarina - IFSC, 88075010, Florianópolis, SC, Brazil.

 

Silvio Atilio Michelin Bertagnolli
Universidade Federal de Santa Maria - UFSM / Hospital Universitário de Santa Maria - HUSM, 97105-900, Santa Maria, RS, Brazil.

 

Thiago Victorino Claus
Universidade Franciscana - UFN/Hospital Universitário de Santa Maria - HUSM, 97105-900, Santa Maria, RS, Brazil.

 

Please see the book here :- https://doi.org/10.9734/bpi/msraa/v12/6367