Calcinosis Cutis as a Rare Complication of Acne Vulgaris |Chapter 8 | Medical Science: Updates and Prospects Vol. 1

 

Introduction: Calcinosis cutis is a rare complication characterized by abnormal deposition of calcium salts in the skin and subcutaneous tissue. While acne vulgaris is a common dermatologic condition marked by comedones, papules, pustules, and nodules, its typical complications include post-inflammatory hyperpigmentation and scarring. Calcinosis cutis secondary to acne is an uncommon and underrecognized entity.

 

Case Presentation: We report the case of a 30-year-old woman with a longstanding history of skin-colored papules localized to the cheeks. Initially diagnosed with comedonal acne, she was treated with isotretinoin (30 mg/day) for over three months without clinical improvement. Physical examination revealed multiple firm, skin-colored papules (2–6 mm) over both cheeks. Closer inspection using a magnification lens revealed no comedones, prompting reconsideration of the diagnosis. Radiographic imaging confirmed the presence of soft tissue calcifications in the affected areas. Laboratory investigations, including serum calcium, vitamin D, parathyroid hormone, and antinuclear antibody levels, were within normal limits. The diagnosis of calcinosis cutis was established, and the patient underwent successful surgical excision of the calcium deposits under local anesthesia.

 

Discussion: This case highlights calcinosis cutis as an unusual yet important complication of acne vulgaris. It typically arises in areas with chronic inflammatory lesions and may mimic persistent acne clinically. Accurate diagnosis requires a combination of detailed clinical examination and imaging studies. Surgical excision remains an effective treatment in localized cases.

 

Conclusion: Calcinosis cutis is an uncommon complication of acne vulgaris and should be considered in patients with long-standing acne-like skin lesions and poor response to conventional anti-acne medications.

 

 

Author(s) Details

Qais Nouri Zghair
Private Clinic, Muscat, Oman.

 

Please see the book here :- https://doi.org/10.9734/bpi/msup/v1/6524

 

Platelet-Rich Plasma for the Management of Acne Scars | Chapter 3 | Medical Science: Recent Advances and Applications Vol. 12

 

Acne vulgaris is one of the most common dermatological disorders, affecting approximately 80–85% of adolescents and young adults worldwide. Major complications of acne include scarring as well as psychosocial distress, which can persist long after the active lesions have resolved. Its onset in adolescence may add to the emotional and psychological challenges experienced during this developmental stage, potentially affecting body image, socialisation, and sexuality. Platelet-rich plasma (PRP) has emerged as a valuable tool in the management of acne scars, offering a safe, autologous, and minimally invasive option that harnesses the body’s regenerative potential. Its efficacy is most evident when used in combination with procedures such as microneedling, fractional CO₂ laser, and subcision. By promoting collagen remodelling, angiogenesis, and epidermal regeneration, PRP addresses the core pathophysiology of scarring.

 

However, the lack of standardised preparation protocols, variability in outcomes, and limited large-scale randomised trials remain challenges. Future advances in biologically enhanced PRP formulations, integration with regenerative medicine, and development of standardised guidelines are likely to strengthen its role in aesthetic dermatology. For now, PRP represents a promising adjunctive modality that bridges the gap between conventional procedures and next-generation regenerative therapies for acne scars. This review briefly discusses the role of PRP in the management of acne scars.

 

 

Author(s) Details

 

Sweta S Kumar
Department of Dermatology, UPUMS Saifai, India.

 

Monika Srivastava
Department of Anatomy, UPUMS Saifai, India.

 

Nisha Yadav
Department of Anatomy, UPUMS Saifai, India.

 

Sanjay Kannaujia
Department of Pathology, UPUMS Saifai, India.

 

Santosh Kumar
Department of Respiratory Medicine, ASMC Etah, India.

 

Utkarsh Tripathi
Department of Dermatology, UPUMS Saifai, India.

 

Please see the book here :- https://doi.org/10.9734/bpi/msraa/v12/6259

Risk Factor and Determine Epidemiology of Acne Vulgaris | Chapter 4 | Current Innovations in Disease and Health Research Vol. 4

 Acne vulgaris is a extensive skin condition that affects a meaningful portion of the population, particularly all along adolescence. This study proposed to assess the distinguishing risk factors and decide the epidemiology and etiology of Acne Vulgaris. A total of 300 victims were included in the study, accompanying 38.67% being males and 61.33% women affected by Acne Vulgaris. The mean age of the affected things was found expected 21.77±4.06 years. The study further examined public habits and found that subjects consumed more hot beverage made from beans of a tree (49.67%) compared to intoxicating (24.67%), smoking (15.33%), and tobacco (5.67%). Additionally, 32.33% of cases had a history of seborrheic rash, which maybe a contributing determinant to the development of acne. Using the Global Acne Grading System (GAGS) scale, the study raise that 94% of patients endured from moderate acne, while 6% endured from severe blemishes. The severity of acne was noticed to be taller in males than women. The most common site for blemishes vulgaris was the face, and the most average types of lesions were comedones and papules. Furthermore, the study identified stress all at once of the major annoying factors for the severity of blemishes vulgaris. This suggests that subjective factors concede possibility play a role in the development and progress of the condition. In conclusion, this study provides valuable understandings into the epidemiology and risk determinants associated with blemishes vulgaris. It highlights the predominance of blemishes in females all along adolescence and in men during adulthood, in addition to the influence of social clothings and stress on its asperity. The findings enhance a better understanding of acne vulgaris and may aid in the happening of more targeted stop and treatment policies for this common skin disease.

Author(s) Details:

Rajesh Hadia,
Department of Pharmacy Practice, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.

Please see the link here: https://stm.bookpi.org/CIDHR-V4/article/view/11446

A Detailed Review on Acne vulgaris | Chapter 9 | Novel Aspects on Pharmaceutical Research Vol. 2

 This study focuses on the causes and situations options for blemishes vulgaris. The most well-known pilosebaceous follicle skin condition, blemishes vulgaris is characterized by papules, knobs, growths, comedones, pustules, and routine scars that are primarily dispersed apparently, middle, and upper back. Inflammation of pimples is a universal skin condition that affects people of all ages. The grandam-positive anaerobic germ Propionibacterium acnes, which is regarded as discharge-planning microorganisms, causes inflammation of the skin.  For the situation of inflammation of the skin, several therapeutic plant parts and dermatological drugs are used.  The pillar of treatment for topical professionals includes benzoyl whiten, anti-infection cures, retinoid, and others; they concede possibility be administered in combination. Systemic situation, which contains isotretinoin, hormonal therapy, and oral antagonistic-microbials, must be chosen established the needs of the patient. Photographic assistance is also constructive for them when taking physical therapy for the sort of harm evacuation. They eventually meet treating dermatologists cause there are numerous established and cutting-edge local and systemic experts usable to treat acne vulgaris.

Author(s) Details:

T. V. Kadam,
Department of Pharmaceutics, K.V.N. Naik Shikshan Prasarak Sanstha’s, Institute of Pharmaceutical Education and Research, Canada Corner, Nashik, Maharashtra, 422002, India.

A. B. Darekar,
Department of Pharmaceutics, K.V.N. Naik Shikshan Prasarak Sanstha’s, Institute of Pharmaceutical Education and Research, Canada Corner, Nashik, Maharashtra, 422002, India.

Please see the link here: https://stm.bookpi.org/NAPR-V2/article/view/10602

Acne Vulgaris: A Brief Review | Chapter 1 | Current Aspects in Pharmaceutical Research and Development Vol. 1

 This review will examine the epidemiology, aetiology, pathophysiology, categorization, and treatment choices for acne vulgaris. Acne is a complex, polymorphic inflammatory disorder that affects the pilosebaceous gland and causes skin lesions. When a youngster hits puberty, the process begins. Interference with the sebaceous gland, which has been related to hyperseborrhoea, hormone imbalance, and other conditions. Interaction of the microenvironment with neucleopeptide, variations in sebum fatty acid content, follicular hyperkeratinizations, innate and adaptive immune dysfunction, and inflammation induction are all critical factors in the development of acneiform. Allopathic, ayurveda, and homoeopathic medicine systems all have an impact on acne vulgaris treatment.

Author(s) Details

Mr. Shailendra Kumar Yadav
Hygia Institute of Pharmaceutical Education and Research, Lucknow, (U.P.), India.


View Book :- https://stm.bookpi.org/CAPRD-V1/article/view/3292