Atherogenic Indices as Biomarkers of Cardiovascular Risk in Obesity | Chapter 13 | New Advances in Medicine and Medical Science Vol. 5

 In the study, we analyzed the unions of anthropometric indices, lipids and atherogenic indices, in corpulent subjects. The demonstrative utility of the atherogenic indications was examined to evaluate the cardiovascular risk in the obese subjects. Major cause of dyslipidemia is corpulence, which should a major strength problem and is raise to be prevalent in two together developed and in underdeveloped countries.A prospective case control study was administered which included cases who accompanied outpatient area of obesity hospital and their accompanying attendants and the stick of Sri Venkateswara Institute of Medical Sciences, Tirupati, India.The dyslipidemia observed in the judgments of the ICMR-INDIAB study found 13.9% of the society had hypercholesterolemia, 29.5% had hypertriglyceridemia, 72.3% had low HDL-C, 11.8% had high LDL-C levels and 79% had deformities in one of the lipid limits. Low HDL-C was the most coarse lipid abnormality and in 44.9% of the society studied, it was present as an isolated anomaly. Comparing cases and controls revealed considerably lower HDL, elevated non-HDL cholesterol, CRI-I, II, and AC levels. BMI considerably correlated unfavorably with HDL and favourably with anthropometric calculations, total cholesterol, non-HDL cholesterol, and atherogenic indices. All the atherogenic indications were related to TC and HDL. With prevent values of 3.85 and 2.85, respectively, CRI-I and AC have better sensitivity and precision. CRI-I and CRI-II also have meaningful diagnostic serviceableness. Lowered HDL levels with elevated atherogenic indications in obesity are exhibitive of cardiovascular risk and can hence be thought-out as a cost effective alternate in assessing CVD risk.

Author(s) Details:

K. Durga Mallika,
Department of Biochemistry, Sri Venkateswara Institute of Medical Sciences, SPMCW, Tirupati, Andhra Pradesh, India.

M. M. Suchitra,
Department of Biochemistry, Sri Venkateswara Institute of Medical Sciences, SPMCW, Tirupati, Andhra Pradesh, India.

Mohammed Arslan,
Department of Biochemistry, Sri Venkateswara Institute of Medical Sciences, SPMCW, Tirupati, Andhra Pradesh, India.

Please see the link here: https://stm.bookpi.org/NAMMS-V5/article/view/10873