Wednesday, 3 August 2022

A Case Report on Cystic Hygroma of Arm Treated with OK-432 | Chapter 14 | Current Practice in Medical Science Vol. 5

 

The example of a newborn baby with Down's syndrome who had a cystic hygroma in his left arm and forearm is described in the current study. Cystic hygromas are a type of lymphangioma that commonly develop in the axilla and cervico-facial regions. The main indications for treatment include respiratory distress, recurring infections, or aesthetic concerns. On day one of life, a newborn male neonate with characteristics of Down's syndrome complained of swelling in his left arm and left forearm to the special care nursery (SCN) of our institution. OK-432 was used to treat the baby's left arm edema. However, the patient died at the age of five months from acute sepsis brought on by the gangrene in his left arm and the accompanying meningitis. For the past 20 years, the drug picibanil, also known as OK-432, has been used to effectively treat cystic hygroma. Although nuchal lymphangioma, Turner's syndrome, and Noonan syndrome have all been linked to cystic hygroma, there is proof that the condition affects people with Down's syndrome more commonly. In order to better understand the negative effects of sclerosant therapy, which has the potential to be the best treatment for cystic hygroma, more case controlled studies should be carried out in the future.

Author(s) Details:

Chin Aun Low,
Department of Orthopaedic Surgery, Hospital Tuanku Ampuan Najihah, Kuala Pilah, Malaysia.

Foead Agus Iwan,
Department of Orthopaedic Surgery, Hospital Tuanku Ampuan Najihah, Kuala Pilah, Malaysia.

Please see the link here: https://stm.bookpi.org/CPMS-V5/article/view/7663

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