Wednesday, 6 July 2022

Bioabsorbable Materials for the Future Treatment of Congenital Heart Disease | Chapter 17 | Current Practice in Medical Science Vol. 2

With a focus on the current state of regenerative engineering valves, patches, and regenerative medicine for pulmonary vein stenosis employing bioabsorbable materials, the current study examines the true demands of regenerative medicine from the perspective of paediatric cardiovascular surgery. Bioabsorbable materials made of polymeric compounds have been employed by several regenerative medicine fields to speed up tissue regeneration. Due to their growing potential, these materials are excellent replacements for autologous tissue in cardiovascular applications such valves, patches, sutures, vascular grafts, and defect occlusion devices in the treatment of congenital heart disease. Between their theoretical benefits and actual practical use in congenital heart disease, there is still a substantial gap. Before using these resorbable, synthetic materials in human therapeutic settings, it is crucial to establish their effectiveness and safety in large animal models.


Author(s) Details:

Yuichi Matsuzaki,
Center for Regenerative Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA.

Toshiharu Shinoka,
Center for Regenerative Medicine, The Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, USA and Department of Cardiothoracic Surgery, The Heart Center, Nationwide Children’s Hospital, Columbus, OH, USA.

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