Background: The current situation has limited the use of antibiotics in a variety of preventive options due to the advent of antibiotic resistance and its negative effects. Indeed, certain innovative tactics and alternative therapies, such as herbal medications and laser therapies, have already reduced the usage of antibiotics in the prevention and treatment of health problems and dental disorders. Many authors are currently striving to demonstrate the role of synbiotics in the preservation of oral health, hence this study looked into synbiotic use and advantages in the post-extraction tooth socket.
The goal of this study is to determine the clinical efficacy and cost-effectiveness of synbiotics versus antibiotics and analgesics in the post-extraction of tooth sockets.
Materials and Procedures: This study was undertaken in three locations in Lucknow, India, including the BBD dental college of dental sciences, as a randomised controlled trial, parallel group, multicenter trial examining the effectiveness of synbiotics in post-extraction socket repair. There were three groups, each with 80 patients. The key outcome measures were observed in each group on the third, fifth, and seventh days.
Results: We identified a substantial difference between the three groups in terms of the examined parameters. The distribution of age and gender is seen in Table 1. Wound-related problems at the surgery site, such as bleeding, edoema, and disruption of gut flora, were more common in groups 2 and 3 than in group 1, which was statistically significant with p values of 0.02, 0.01, and 0.01. Table 5 shows the cost analysis of the study subjects during treatment, with statistically significant findings obtained at p 0.01 between groups 1 and 2, group 1 and 3, and group 2 and 3. Conclusion: Because this was a novel way of comparing post-extraction wound healing, the results showed that synbiotics had a distinct favourable effect. Synbiotics have the potential to improve dental health. Before putting the product into clinical use, more research with a larger sample size and a different formulation is recommended.Author(S) Details
Shweta Singh
Department of Public Health Dentistry, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India.
S. Sahana
Department of Public Health Dentistry, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India.
Sulabh Kumar
Department of Prosthodontics, Babu Banarasi Das College of Dental Sciences, Lucknow, Uttar Pradesh, India.
N. K. Gupta
Mayo Hospital, Lucknow, Uttar Pradesh, India.
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