Showing posts with label polymers. Show all posts
Showing posts with label polymers. Show all posts

Monday, 25 August 2025

Doping of Poly (3,4-ethylenedioxythiophene) (PEDOT) by FeCl3 | Chapter 9 | Chemical and Materials Sciences: Research Findings Vol. 4

 

Academic and industrial researchers have focused on developing conducting polymers that are stable in their conductive state during application, easy to process, and economical to produce. Conducting polymers, often referred to as synthetic metals, have garnered significant attention since Shirakawa and colleagues discovered that polyacetylene can achieve exceptionally high electrical conductivity. The study aims to investigate the structural, electrical, and thermal properties of the resulting material. Poly(3,4-ethylenedioxythiophene) (PEDOT) has been chemically synthesised using 3,4-ethylenedioxythiophene (EDOT) (Aldrich) as a monomer in an aqueous solution with FeCl3 as the oxidant. Doping of PEDOT using Camphor Sulfonic Acid (CSA) and FeCl3 was carried out separately for a 5-hour duration, and the resulting material was then subjected to various analyses. To detect structural changes after doping, infrared spectroscopic analysis, wide-angle x-ray diffraction analysis have been carried out. Elemental analysis (C, H, N, S, and O) of undoped and all doped samples was carried out using Thermofinniagn, Italy, model FLASH EA 1112 series, and ICP - Atomic Emission Spectroscopy made by Jobin Yvon, France, model JY Ultima–2 was used to detect Fe contents in all samples. PEDOT has been chemically synthesised by oxidation, coupling with FeCl3 as an oxidation reagent, and then treated with hydrazine to de-dope the prepared polymer. For complete confirmation, FTIR spectroscopy studies were carried out. The results of thermal analysis show that after doping PEDOT with FeCl3, the glass transition temperature (Tg) value decreases. It is observed that in the case of FeCl3-doped PEDOT, sulfur contents decrease while Fe contents increase compared to undoped PEDOT, indicating that it is quite likely that the S of PEDOT is getting replaced by Fe after doping with FeCl3. The utilization of FTIR analysis verified the successful synthesis of PEDOT, as well as the desired doping with FeCl3 and CSA. The crystal structure of the samples was analyzed using XRD, revealing modifications following doping. Additionally, the XRD results allowed for the calculation of sample crystallinity, which increased after doping with FeCl3 but decreased after doping with CSA. Using the four-probe method, electrical conductivity (σ) measurements were obtained, showing a significant increase in conductivity after doping with both FeCl3 and CSA, with the undoped sample having a conductivity of 3.41X10-3S/cm. A plot of Log σ versus 1/T was created, revealing that the undoped PEDOT had metallic characteristics above 308 K, while both doped samples displayed semiconducting behavior in the temperature range from ambient to 383̊ K. An indigenously designed apparatus similar to Lee's method was used for measuring the thermal conductivity, which revealed that all samples exhibited comparatively small thermal conductivity values. However, these values were found to increase upon doping and with a temperature rise. The thermal conductivity of all the samples was also measured using the FOX 50 instrument, a commercially available apparatus for the measurement of thermal conductivity. The values of thermal conductivity of all the samples were found to match the laboratory-designed instrument.

 

Author(s) Details

Ashish B. Chourasia
Department of Electronic Science, H.P.T. Arts and R.Y.K. Science College, Nashik-422 005, India.

Deepali S. Kelkar
Department of Physics, Govt. Institute of Science, Nagpur, India.

 

 

Please see the book here:- https://doi.org/10.9734/bpi/cmsrf/v4/6074

Friday, 18 July 2025

Mucoadhesion: A Potential Approach in Site Specific and Targeted Drug Delivery | Chapter 2 | Medical Research and Its Applications Vol. 11

Mucoadhesive drug delivery system (MDDS) is a promising approach for targeted drug release. It addresses the bioavailability issues of pharmaceutical dosage forms i.e., remaining at their absorption site for an inadequately short time. Mucoadhesive dosage forms adhere to mucosal surfaces and offer various advantages including prolonged drug residence time, enhanced drug absorption, and localized drug delivery. Novel mucoadhesive polymers, including natural, synthetic, and semi-synthetic materials that improve mucoadhesive properties and biocompatibility were discussed in this review. Formulation and designing of nanoparticles, liposomes, and micelles with a mucoadhesive approach enables targeted drug delivery and controlled release profiles. The key considerations for drugs suitable for mucoadhesive drug delivery are poorly soluble, short half-life, and sensitivity to gastric environment. This review comprehensively explains the mechanism, theories, advantages, and recent advancements in mucoadhesive drug delivery.

 

Author(s) Details

Rajeswari Aleti
Department of Pharmaceutics, Gokaraju Rangaraju College of Pharmacy, Hyderabad 500090, India.

 

Pavan Kumar Thota
Department of Pharmaceutics, Gokaraju Rangaraju College of Pharmacy, Hyderabad 500090, India.

 

Monika Nijhawan
Department of Pharmaceutics, Gokaraju Rangaraju College of Pharmacy, Hyderabad 500090, India.

 

Bhavana Jidige
Department of Pharmaceutics, Gokaraju Rangaraju College of Pharmacy, Hyderabad 500090, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mria/v11/1427

Wednesday, 5 March 2025

Unlocking New Possibilities: A Review of Applications and Benefits of Nanofibers | Chapter 5 | Pharmaceutical Science: New Insights and Developments Vol. 1

Nanotechnology is a rapidly developing discipline that has the promise to significantly impact the global economy and science. Researchers are increasingly emphasizing the development of nanomaterials for a wide range of applications. Nanofibers have emerged as intriguing one-dimensional nanomaterials for many research and commercial applications due to their unique physicochemical properties and characteristics.  They have a significant surface-to-volume ratio and can create a network of extremely porous mesh. The intricate network of the pores makes them a great candidate for several innovative applications particularly in the biomedical field. Various natural and semi-synthetic polymers are utilized to produce nanofibers based on their intended application. Nanofiber composites serve as an effective alternative for targeted gene delivery, protein, peptide administration, and growth factor delivery. Nanofibers may be utilized across several therapeutic fields and potentially transform them owing to their extensive drug transport capabilities. This chapter examines the fundamental notion of nanofibers, including their benefits, drawbacks, and applications.

 

Author (s) Details

 

Vaishali Bharat
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

S.K. Lanjhiyana
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

Sanjay Kumar Bharti
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

Alpana Ram
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

Nidhi Agrawal
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

Rashmi Dewangan
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

Meenakshi Jaiswal
Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur (C.G)-495009, Chhattisgarh, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/psnid/v1/3545

Thursday, 6 February 2025

Revolutionizing Material Science: The Impact of Polymeric Nanocomposites | Chapter 1 | Exploration of Knowledge and Information in Sciences

The field of materials science has been revolutionized by the introduction of polymer nanocomposites, which combine the unique properties of polymers and nanoscale fillers to create materials with superior functionalities. The integration of nanoscale fillers into polymer matrices has led to significant advancements in mechanical, thermal, electrical, and barrier properties. This chapter provides a comprehensive overview of polymer nanocomposites, discussing their classification, synthesis methods, characterization techniques, and diverse applications in industries such as automotive, aerospace, electronics, and packaging. Additionally, this study addresses the challenges in the development of these materials and explores future research directions, highlighting their potential to further enhance material performance.

 

Author (s) Details

 

Puneet Gupta
Department of Physics, S. A. Jain (P. G.) College, Ambala City, Haryana, India.

 

Anil Tomar
Department of Physics, S. A. Jain (P. G.) College, Ambala City, Haryana, India.

 

Please see the book here:- https://doi.org/10.9734/bpi/mono/978-93-48859-02-0/CH1

Saturday, 13 January 2024

A Comprehensive Review on the Versatile Applications of Ionic Liquids | Chapter 4 | Current Innovations in Chemical and Materials Sciences Vol. 4

 This review item highlights the miscellaneous applications of Ionic fluids (IL) such as solvent, electrolytes, catalysis, solar cells, fuel containers, polymer science, snack and bioproducts, lubricants, and many more ILs are also known as salts they are appropriate to beneath melting point and they maybe also considered as a novel and particular set of solvents. ILs are as well just green solvents and they showed interest in allure practically discrediting. They have established several requests and they synthesized water and air-resistant ionic liquids established an imidazolium cation like 1-alkyl-3-methylimidazolium and also tetrafluoroborate or hexafluorophosphate as the anion. The review is an attempt to give notice of possible occurrence of the usage of Concerning ancient culture liquids in various fields and remember the application of ILs in additional fields also based on their features. Finally, it is decided that ILs have various applications indifferent fields such as use as solvent in various industries, electrolytes, assorted catalysis, solar containers, fuel cells, polymer industry, foodstuff and bioproducts, and lubricants. However, few drawbacks with concerning ancient culture liquids are emphasize concerning toxicity, preparation, and extreme cost in the process for use.

Author(s) Details:

Srinivasa Rao Aangothu,
Department of Chemistry, Acharya Nagarjuna University, Guntur- 522510, AP, India.

Sowjanya Prathipati,
Department of Chemistry, Acharya Nagarjuna University, Guntur- 522510, AP, India.

J. N. Pavan Kumar Chintala,
Department of Physics, Sir C.R.R. College, Eluru, W.G. Dist., AP, India.

Soumini C.,
Department of Chemistry, M.E.S Ponnani College, Ponnani, Kerala, India.

Hari Babu Bollikolla,
Department of Chemistry, Acharya Nagarjuna University, Guntur- 522510, AP, India.

Please see the link here: https://stm.bookpi.org/CICMS-V4/article/view/12933

Synthesis of Uniform and Strongly Adherent Poly (Aniline-co-o-toluidine) Copolymer Coatings on Copper | Chapter 3 | Current Innovations in Chemical and Materials Sciences Vol. 4

 The uniform and powerfully adherent poly(aniline-co-o-toluidine) (PAOT) copolymer coatings were synthesized on law enforcement officer (Cu) by the electrochemical copolymerization of aniline accompanying o-toluidine. Also the individual polymer i.e. polyaniline (PANI) and polytoluidine (Cauldron) coatings were synthesized on Cu under cyclic voltammetric environments. Aqueous oxalate answers were used as the supporting electrolytes for the combining of PAOT, PANI and POT coatings on Cu. The happening coatings were characterized by different spectroscopic methods, cyclic voltammetry, ultraviolet–visible absorption spectroscopy, Fourier translate infrared spectroscopy (FTIR), basic magnetic resonance spectroscopy (NMR), and flipping through electron microscopy. The comparative study of description results was carried out of PAOT5, Container and PANI coatings.The Fourier Transform Infra Coral (FTIR) spectroscopy and Nuclear Magnetic Reverberation (NMR) spectroscopy studies reveal that the copolymerization of aniline and o-toluidine takes establish Cu substrates from an aqueous oxalate solutions and happening in PAOT copolymer, there are more o-toluidine wholes than aniline units.

Author(s) Details:

Pritee Raotole,
MGSM’s Arts, Science and Commerce College, Chopda, Dist-Jalgaon 425107, Maharashtra, India.

S. R. Patil,
MGSM’s Arts, Science and Commerce College, Chopda, Dist-Jalgaon 425107, Maharashtra, India.

Please see the link here: https://stm.bookpi.org/CICMS-V4/article/view/12932

Monday, 21 August 2023

Sustained Release Matrix Tablet of Cisapride Drug to Treats Heartburn Caused by Gastroesophageal Reflux Disease (Gerd): A Detail Study Including Formulation, Evaluation and Optimization Aspects | Chapter 1 | Novel Aspects on Pharmaceutical Research Vol. 8

Aim and Objective: Aim of present work search out prepare and judge sustained release matrix dose of cisapride, due to short half history it is ideal candidate of maintained release drug delivery plan and reduce the frequency of presidency and to improve patient agreement. Dose of drug is 20 mg thrice a day by planning sustained release cast tablet using hydrogel polymers we can humble once a day accompanying better therapeutic belongings.   Materials and Methods: Direct compression arrangement was used to formulate tablets, two polymers HPMC K4M and HPMC K100M using in expression development. After form tablet readiness, tablet was judged with many tests including artificial disintegration, separation and FTIR. 32 full factorial designs were achieved for optimizing formulation attended by kinetic analysis and strength study of optimized expression.Results and Discussion: Consequences of Preformulation research of the Cisapride indicate that it has weak float property and compressibility property. To improve the drift and compressibility property, it enhanced useful to use the immediately compressible grade additives inside the formulation of tablet. Consequences of DSC test proven that skilled's no exchange in drug’s melting peak following in position or time the education of dose. Hydrophilic matrix of HPMC K4M and HPMC K100M in mixture maintained the Cisapride release effectively for as well 12h. The end result indicates that the combination of HPMCK4M and HPMCK100M may be right, On the idea of the initial troubles in the present examine a32 full factorial design exchanged into hired to scrutinize at the effect of unbiased variables, i.e. awareness of HPMCK4M(X1) and consideration of HPMCK100M(X2) on dependent variables like% drug begin Q2, Q6 and Q10. Drug launch is likewise depending on the scale of cast capsules so, size and surface location was stocked consistent. Factorial bundles F018, F019, F020, and F021 supply the f2 value seventy five-100. Factorial amount F019 offers the very best f2 payment 86.04 and also all of the hour’s drug release was within the guide limits.Conclusion: The prepared expression of Cisapride sustains release forge tablet was fixed and effective in treatment.

Author(s) Details:

Darshit Ram,
Faculty of Pharmacy, Noble University, Junagadh, 362001, Gujarat, India.

Santosh Kirtane,
Faculty of Pharmacy, Noble University, Junagadh, 362001, Gujarat, India.

Rukhshar Khilji,
Faculty of Pharmacy, Noble University, Junagadh, 362001, Gujarat, India.

Priyanka Miniya,
Faculty of Pharmacy, Noble University, Junagadh, 362001, Gujarat, India.

Jagruti Bheda,
Faculty of Pharmacy, Noble University, Junagadh, 362001, Gujarat, India.

Please see the link here: https://stm.bookpi.org/NAPR-V8/article/view/11648

Monday, 24 July 2023

Resistance of Natural Fiber Reinforced Polymer Composites in Tropical Environments | Chapter 4 | Current Topics and Emerging Issues in Materials Sciences Vol. 2

 The aim concerning this study is to investigate the depravity mechanism of normal fiber-reinforced polymer composites in equatorial environments.The use of polymer matrix composites supported by natural fibers is growing due to their high particular strength and stiffness, reduced manufacturing costs, disintegration resistance and abundant chance of raw materials. However, polymer matrix composites have depressed weather resistance when used outdoors which are straightforwardly exposed to sunlight, rain, variable temperatures and air holding pollutant particles. This condition frequently occurs in tropical districts which are characterized by extreme intensity of light part of every 24 hours and rainfall and an atmosphere that holds a lot of dust. This chapter reviews the mechanism of shame of natural fiber supported polymer composites in tropical climates. By understanding this mechanism, it is attainable to determine the existence of the composite component and the appropriate protection method to increase the history of the component.

Author(s) Details:

Wahyu Purwo Raharjo,

Department of Mechanical Engineering, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia and Research Group of Nonmetal Materials Technology and Processing, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia.

Dody Ariawan,

Department of Mechanical Engineering, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia and Research Group of Nonmetal Materials Technology and Processing, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia.

Kuncoro Diharjo,

Department of Mechanical Engineering, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia and Research Group of Nonmetal Materials Technology and Processing, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia.

Wijang Wisnu Raharjo,

Department of Mechanical Engineering, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia and Research Group of Nonmetal Materials Technology and Processing, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia.

Bambang Kusharjanta,

Department of Mechanical Engineering, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia and Research Group of Nonmetal Materials Technology and Processing, Faculty of Engineering, Universitas Sebelas Maret, Surakarta, Indonesia.

Please see the link here: https://stm.bookpi.org/CTEIMS-V2/article/view/11298

Wednesday, 18 January 2023

Evaluating the Pharmacokinetic of Spray Dried Paliperidone Composition in Rats| Chapter 1 | Current Overview on Pharmaceutical Science Vol. 3

 Spray drying whole operations are used to produce drained powder across a wide range of material deal with applications from food to manure to pharmaceuticals.  In this chapter, pharmacokinetics of spray drained composition (1:1 PAL: K12) and clean PAL was evaluated following spoken administration (0.8 mg/kg) in healthful female Sprague Dawley rats. The extent of mean plasma PAL exposure was 11-fold better in animals doctored with a spray drained mixture of PAL, K12 (1:1) than in mammals treated accompanying PAL. Spray drying PAL with Plasdones, particularly Plasdone K12, decreased crystallinity and improved bioavailability.

Author(s) Details:


A. Pandey,
Himgiri Zee University, Deharadun, Uttarakhand 248197, India.

Please see the link here: https://stm.bookpi.org/COPS-V3/article/view/9106

Wednesday, 16 March 2022

Treatment of Skin Wounds in Old Animals Using Mesenzymal Progenitor Cells and Polymer Gel Compositions| Chapter 14 | Issues and Developments in Medicine and Medical Research Vol.11

The goal of this study was to see how successful progenitor mesenchymal stem cells were as injections and as part of a polymer hydrogel for wound healing in elderly animals.

Materials and Methods: On the backs of 9-month-old white Wistar rats, fixed-size wounds (average area of 135.8 mm2) were simulated. On the day of the modelling, MSC were extracted from a human umbilical cord and injected into the wounds once (SC group). MSC were administered externally on a regular basis as one of the components of the polymer hydrogel in other animals (Polymer sc group). Examining undamaged contralateral wounds on the opposite side of the same animal's back was used to assess the cells' systemic effect (control sc and Control Psc groups, respectively). The Control 0 group included the intact reference wounds. Dynamic analysis of the wound region was carried out. The collagen fibres' maturity, the epidermal layers, and the number of fibroblasts and leukocytes in different regions of the wounds were all assessed using descriptive microscopy.

The administration of MSCs, both locally and systemically, promoted wound repair. During the acute inflammatory phase, the method and site of application had little effect on the dynamics of wound healing (up to 3 days). Polymer sc was shown to be the most effective in the end. A reduction in leukocyte infiltration in wound centres (Polymer sc and SC groups) and edges (all groups, with the greatest extent in the Polymer sc group) indicated MSC's anti-inflammatory impact. The proliferative phase, which shows itself as increased fibroblast number and collagen production, was observed in the Control Psc group, particularly in the Polymer sc group.

Conclusion: MSC therapy improves and speeds wound healing in a variety of ways, even in elderly animals. In the Polymer sc category, the best results were achieved.

Author(s) Details:

Natalia Manturova,
Department of Plastic and Reconstructive Surgery, Cosmetology and Cell Technologies, Pirogov Russian National Research Medical University, Moscow, Russia.


Victor Stupin,
Department of Hospital Surgery no 1, Pirogov Russian National Research Medical University, Moscow, Russia.


Ekaterina Silina,
Institute of Biodesign and Modeling of Complex Systems, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Please see the link here: https://stm.bookpi.org/IDMMR-V11/article/view/6086

Thursday, 3 March 2022

Role of Polysaccharides in Advancement of Pharmaceutical Sustained and Controlled Release Dosage Forms | Chapter 1 | Current Aspects in Pharmaceutical Research and Development Vol.9

 The purpose of this article is to provide an overview of the critical function of a few polysaccharides in the creation of innovative sustained and controlled-release dosage forms containing therapeutic candidates (s). Polymers have played a significant role in the improvement of drug delivery technologies in the biomedical, tissue engineering, and pharmaceutical industries over the last few decades. It was because of the polymers' special tuneable physicochemical features that allowed for changed drug release patterns from both traditional and innovative dosage forms. Because of their unique pH responsiveness, biodegradability, biocompatibility, non-immunogenic, solubilization, and non poisonous qualities, those modified delivery systems were able to offer regulated and sustained releases of drug(s) into the neighbourhood of the specified area of interest. In this article, we've tried to highlight a few polymers for their physicochemical properties, molecular structures, and mechanisms of action, as well as their potential for use in the creation and development of dosage forms in our pharmaceutical industries.

Author(s) Details:

S. K. Lanjhiyana,
Pharmaceutics Research Division, Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (Central University), Bilaspur (C.G.) - 495009, India.

Sanmati K. Jain,
Pharmaceutics Research Division, Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (Central University), Bilaspur (C.G.) - 495009, India.

Sweety Lanjhiyna,
School of Pharmacy, Chouksey Engineering College, Bilaspur (C.G.)- 495001, India.

Bharti Ahirwar,
Pharmaceutics Research Division, Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (Central University), Bilaspur (C.G.) - 495009, India.

A. C. Rana,
Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, Haryana, India.

Please see the link here: https://stm.bookpi.org/CAPRD-V9/article/view/5961

Thursday, 3 June 2021

Polymer/steel Tribological Characteristics and Corrosion and Under External Voltages | Chapter 2 | Advanced Aspects of Engineering Research Vol. 11

 Metals are constantly in contact with their environment, whether it is air, vapour, water, or other chemicals, resulting in chemical interactions between metals and their respective environments, resulting in an insidious localised form of corrosion that causes much devastating destruction to structural members such as stainless steel in H2SO4 environments. The corrosion activity was studied using weight loss studies. The current study investigates the effects of three types of oil-dispersed polymers on the abrasive sliding wear of stainless steel: low-density polyethylene (LDPE), high-density polyethylene (HDPE), and polysulphide rubber (PSR). The external voltage enhances both the friction coefficient and the wear scar diameter, with PSR having a smaller scar diameter than both LDPE and HDPE. For all applied polymers, negative applied voltage has a smaller scar diameter than positive applied voltage. HDPE has the highest wear rate trends, followed by LDPE and PSR, in that order. The metallographic study revealed that when the H2SO4 solution interacts with the surface of the specimen, it causes pitting corrosion, weakens it, damages it, and changes its roughness over time.

Author (s) Details

S. A. Al-Ghamdi
Department of Electrical Engineering, Faculty of Engineering, Albaha University, Kingdom Saudi Arabia.

H. Abo-Dief
The Egyptian Petroleum Research Institute, Nasr City, Cairo, Egypt and The Chemistry Department, Faculty of Science, Al-Taif University, Kingdom of Saudi Arabia.

A. T. Mohamed
Mechanical Engineering Department, Albaha Faculty of Engineering, Albaha, Kingdom of Saudi Arabia.

View Book : https://stm.bookpi.org/AAER-V11/article/view/1242

Thursday, 5 November 2020

Swelling and Drug Release Studies from Hydrophilic Matrices Containing Combination of Different Grades of Hydroxyl Propyl Methylcellulose | Chapter 6 | Trends in Pharmaceutical Research and Development Vol. 5

 In formulating sustained release tablets, polymers are very common and commonly used because they are excellent drug carriers. The current research explores the release of drugs from hydrophilic matrices prepared using a mixture of hydroxyl propyl methylcellulose (HPMC), HPMCK4 M, HPMCK15 M and HPMCK100 M grades. The findings suggest that the concentration and viscosity grades of the polymer were influenced by the swelling and release profiles. The rate of water absorption into the matrices regulates this swelling action of HPMC of different grades in turn. The drug release rate and the matrix-swelling rate have an inverse relationship. This means that the rational combination of the various grades appears to provide a reasonably controlled drug release. Therefore, in predicting drug release, the swelling behaviour is useful.


Author(s) Details

Dr. Masheer Ahmed Khan
School of Pharmacy, Devi Ahilya Vishwavidyalaya, Takshshila Campus, Khandwa Road, Indore, 452001, India.

Prof. S. C. Chaturvedi
School of Pharmacy, Devi Ahilya Vishwavidyalaya, Takshshila Campus, Khandwa Road, Indore, 452001, India.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/303

Wednesday, 26 August 2020

Engineered Nanoparticles in Environmental Mitigation and Green Growth | Chapter 2 | Recent Advances in Science and Technology Research Vol.4

 

The notion of green growth has emerged as a dominant policy response to climate change and

ecological breakdown. Environmental contamination is one of the important issues that the world is

facing today, it is always expanding and leading to the grave and harmful effect on the Earth.

Nanoparticles have a diameter less than 100 nm exhibit new size-dependent properties compared

with the bulk material. Engineered nanoparticles (ENPs) have unique characteristics in addition to the

high surface area-to-volume ratio, which may increase their toxicity relative to bulk materials. Due to

the high volume production of ENPs products such as carbon nanotubes, titanium dioxide, silver, zinc

oxide environmental exposure to these compounds is very common. ENPs have their unique

properties and applications in the areas of medicine, food & drink, construction, automotive, textiles,

energy, electronics, environment etc. To enable society to build and sustain a green economy, the

associated concept of “green nanotechnology” aims to exploit nano-innovations in materials science

and engineering to generate products and processes that are energy efficient as well as economically

and environmentally sustainable. The present book chapter is focused on the recent development of

the applications of ENPs in the environmental mitigation and green growth.

Author (s) Details

Brij Bhushan Tewari

Department of Chemistry, Faculty of Natural Sciences, University of Guyana, P.O. Box 101110, Georgetown, Guyana.

 

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/240