The combination of CRISPR (clustered regularly interspaced
short palindromic repeats) gene-editing technology with Artificial Intelligence
(AI) is changing precision medicine by changing the efficiency, accuracy, and
implementation of genetic modification. CRISPR, an inventive instrument for
targeted gene editing, has been widely used in the treatment of genetic
disorders, the discovery of novel medical treatments, and the growth of
personalised medicine. By developing a method to improve the predictability of
gene sequence problems, minimising off-target, minimising error, and developing
accurate target selection. All these types of limitations can be overcome with
the help of AI technology. It provides easy, precise and accurate results. AI
use a previously kept database to help discover feasible gene-editing targets.
By improving guide RNA sequences and minimising off-target interactions, there
is a chance of improving CRISPR specificity. In addition to that, AI
advancements help to predict the gene-editing outcomes, which ultimately help
to reduce the time and cost of the associated preclinical research. This Combination of AI and CRISPR has
developed a new technology in biological science, which gives a more powerful
method for disease treatment and human health. Combination is mainly focused on
the treatment of rare diseases such as Cancer and Sickle cell anaemia. The
study mainly examines and focuses on the recent development of the AI-CRISPR
combination for gene editing, its importance, its impact on precision medicine,
and the future impact of technology in science.
Author(s) Details
Rajat R. Durbule
Department of Quality Assurance Technique, PES Modern College of Pharmacy,
Nigdi-411044, Pune, Maharashtra, India.
Pallavi M. Patil
Department of Pharmaceutical Chemistry, PES Modern College of Pharmacy,
Nigdi-411044, Pune, Maharashtra, India.
Prathmesh B. Parkale
Department of Quality Assurance Technique, PES Modern College of Pharmacy,
Nigdi-411044, Pune, Maharashtra, India.
Shivani L. Bhuse
Department of Pharmaceutical Chemistry, PES Modern College
of Pharmacy, Nigdi-411044, Pune, Maharashtra, India.
Vedant A. Kabra
Department of Pharmaceutics, School of Pharmacy, D.Y. Patil (Deemed to be
University), Navi Mumbai-400706, India.
Please see the book here:- https://doi.org/10.9734/bpi/msraa/v9/6010
