Thursday, 15 January 2026

Dermatological Applications of Punica granatum: Phytochemistry and Therapeutic Potential in Skin Disorders |Chapter 7 | Pharmaceutical Science: New Insights and Developments Vol. 9

 

Pomegranate (Punica granatum) is a popular fruit known for its rich nutritional value and diverse bioactive compounds. The fruit has many potential health benefits, and it has been evaluated in clinical trials for different diseases. There are limited studies investigating the comprehensive use of pomegranate in cosmetic and dermatological applications. This chapter presents a comprehensive review of the dermatological applications and therapeutic potential of Punica granatum, with a focus on its phytochemistry and mechanisms of action. The increasing use of botanical extracts in skincare and cosmetic formulations underscores the relevance of Punica granatum, a plant native to Iran. A structured literature search was conducted across various databases, including PubMed, ScienceDirect, Springer, and Google Scholar, to evaluate evidence from preclinical and clinical studies. Key findings indicate that pomegranate extracts and their bioactive compounds—particularly punicalagin, ellagic acid, and anthocyanins—exhibit significant antioxidant, anti-inflammatory, antimicrobial, and wound-healing properties. Specific dermatological benefits explored include the promotion of wound repair, inhibition of acne pathogenesis, protection against UV-induced photoaging, skin brightening, and management of inflammatory skin conditions such as atopic dermatitis. This review consolidates current scientific research to highlight the promising role of Punica granatum as a multifunctional agent in the treatment and prevention of skin disorders, supporting its continued integration into dermatological and cosmetic products.

 

Author(s) Details

Farshad Akbarnejad
Dr. Akhavi Laboratory Co, Scientific Department, Tehran, Iran.

 

 

Please see the book here :- https://doi.org/10.9734/bpi/psnid/v9/6868

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