Friday, 30 January 2026

Copper-Mediated Cross Coupling Reactions and Their Applications: An Overview | Chapter 2 | Chemistry and Biochemistry: Research Progress Vol. 9

 

Copper (Cu) is a promising catalytic metal for C–C bond construction through coupling transformations. Coupling strategies of a range of organo-metallic reagents, with aromatic, heteroaromatic, and alkyl halides, can be carried out by Cu-catalysts with high efficiency, demonstrating the adaptability of Cu supported catalytic methods in carrying out these transformations. Conversely, the parallel palladium-catalysed cross-coupling methods are frequently complementary to the scope and selectivity of copper-assisted methods. Furthermore, Cu-catalysts are displaying a distinct pattern of reactivity that permits ligand-less coupling for the formation of aromatic–heteroaromatic and heteroaromatic–heteroaromatic bonds, a transformation that typically calls for unique, specially created ligands with Pd-catalysts. Early findings in the field of Cu-mediated couplings to generate C-C bonds are summarised in this chapter.

 

 

Author(s) Details

Gadamani Suresh Babu
Department of Humanities & Sciences, Brilliant Institute of Engineering & Technology, Abdullapur (V), Abdullapurmet (M), R.R District-501505, India.

 

Kiran Kumar Tatapudi
Discovery Analytical R&D Department, Aragen Life Sciences Pvt. Ltd., IDA Nacharam, Hyderabad, Telangana, India.

 

Surinderpal Singh
Department of Chemistry (H&S), CMR Engineering College, Kandlakoya (V), Medchal Road, Hyderabad, Telangana 501401, India.

 

Tiruveedhula Somasekhar
Department of Humanities & Sciences, Vidya Jyothi Institute of Technology, Aziz Nagar Gate, Chilkur Balaji Road, Himayat Sagar Rd, Hyderabad, Telangana 500075, India.

 

Hemambika SadasivuniDepartment of Freshmen Engineering, St. Martin’s Engineering College, Dhulapally, Hyderabad, Telangana-500100, India.

 

S. Ratna Kumari
Department of Chemistry, Basic Science & Humanities, Vignan's Nirula Institute of Technology and Science for Women, Guntur, A.P., India.

 

S N Murthy Boddapati
Department of Chemistry, Sir C R Reddy College, Eluru, Andhra Pradesh-534007, India.

 

 

Please see the book here :- https://doi.org/10.9734/bpi/cbrp/v9/6761

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