Thursday 24 August 2023

Determination of Three-Dimensional Ultrasound Measurement of Fetal Adrenal Gland and Maternal Serum Fructosamine Level in Gestational Diabetes Mellitus: A Prospective Cohort Study | Chapter 13 | Current Progress in Medicine and Medical Research Vol. 7

This branch evaluate the correlation 'tween fetal adrenal gland size and capacity observed utilizing two-dimensional (2D) ultrasound measurement in transverse, crown, and sagittal planes and three-dimensional (3D) ultrasound calculation using virtual means computer-supported analysis (VOCAL) software and motherly serum fructosamine levels in GDM patients. Gestational diabetes mellitus (GDM) has an affect fetal adrenal gland size and capacity, which are greater in girls with GDM distinguished to those without. This prospective comrade study was performed at GDM clinic in Ramathibodi clinic, Mahidol University from January to December 2019. The foetal zone and overall adrenal gland volume in 3D ultrasonography were evaluated using the in essence organ computer-helped analysis (VOCAL) software. Up just before birth, all subjects were listened. The link between foetal adrenal gland ultrasonography measures and the relevant limits was investigated utilizing Pearson's correlation analysis.The study included sixty-six (82.5%) pregnant women accompanying diet-controlled GDM (GDMA1) and 14 (17.5%) with insulin-trained GDM (GDMA2). There was no difference in before birth adrenal gland measurements between the groups. In addition, all members achieved optimal sweet substance levels at the time of ultrasound acquisition.  The judgments of this study display that fetal adrenal gland measurements utilizing 2D and 3D ultrasonography in the third trimester can be visualized and calculated adequately in 96.4%. The total adrenal gland length and before birth zone volume are compared with EFW, motherly fructosamine, and HbA1c levels in well-controlled GDM. The total adrenal gland length and before birth zone volume had statistically meaningful positive correlations accompanying EFW (r = 0.69, p = 0.02 and r = 0.84, p = 0.01, respectively). After regulating for EFW, the relationships of total adrenal gland length accompanying fructosamine levels (adjusted-OR = 0.4, 95% CI: 0.1, 0.7) and HbA1c levels (adjusted-OR = 0.3, 95% CI: 0.1, 0.6) were statistically important (p < 0.05). Likewise, the relationship between before birth zone volume accompanying fructosamine levels (adjusted-OR = 2.4, 95% CI: 1.5, 3.9) and HbA1c levels (regulated-OR = 2.5, 95% CI: 1.6, 4.3) were statistically significant (p < 0.05).The study also found a correlation between EFW, fructosamine levels, and HbA1c levels and total adrenal gland time and foetal zone volume. These non-obtrusive methods maybe useful for GDM patients as glycemic listening indirect markers.

Author(s) Details:

Saowapak Junhasavasdikul,
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Faculty of Medicine, Mahidol University, Ramathibodi Hospital, Bangkok, Thailand.

Panyu Panburana,
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Faculty of Medicine, Mahidol University, Ramathibodi Hospital, Bangkok, Thailand.

Sommart Bumrungphuet,
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Faculty of Medicine, Mahidol University, Ramathibodi Hospital, Bangkok, Thailand.

Wirada Dulyaphat,
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Faculty of Medicine, Mahidol University, Ramathibodi Hospital, Bangkok, Thailand.

Please see the link here: https://stm.bookpi.org/CPMMR-V7/article/view/11668

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