Exploring the Use of Manual Liquid Based Cytology, Cell Block with Immunomarkers p16/ki67, VIA and HPV DNA Testing as a Strategy for Cervical Cancer Screening in LMIC: A Prospective Study | Chapter 12 | Recent Developments in Medicine and Medical Research Vol. 1

 Cervical cancer is the fourth most prevalent cancer in women in low- and middle-income countries (LMIC). Cervical cancer can be detected using a variety of methods, including the traditional Pap smear (CPS), Liquid Based Cytology, and supplemental techniques including Cell Block with immunocytochemistry. The VIA is another technique that is being advocated as a crucial screening tool. Screening efforts have centred on HPV DNA testing and other molecular diagnostics.

All of the following strategies were employed in this study to investigate if they could be useful in clinical settings using cost-effective in-house procedures. In view of the need for more work and personnel training in order to improve cervical cancer diagnosis, we found them useful. There is a need for a standardised policy for screening women at primary health care centres, as well as increased public awareness of the various approaches.

Author(S) Details

Nandini Nandish Manoli
Department of Pathology, JSS Medical College, JSS Academy of Higher Education & Research, 570015, India and Centre of Excellence in Molecular Biology & Regenerative Medicine, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research,570015, India.

Devananda Devegowda
Centre of Excellence in Molecular Biology & Regenerative Medicine, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research,570015, India.

Ashoka Varshini
Department of Pathology, JSS Medical College, JSS Academy of Higher Education & Research, 570015, India.

Pushkal Sinduvadi Ramesh
Centre of Excellence in Molecular Biology & Regenerative Medicine, Department of Biochemistry, JSS Medical College, JSS Academy of Higher Education & Research,570015, India.

Sherin Susheel Mathew
Department of Pathology, Dr. Somervell Memorial Church of South India Medical College, 695504, India.

Nandish Siddappa Manoli
Department of Obstetrics and Gynecology, JSS Medical College, JSS Academy of Higher Education & Research, 570015, India.

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